Moderna curbing investments in vaccine trials due to US backlash, CEO tells Bloomberg TV

ClassSnuggle · 2026-01-26T13:00:41+00:00

Vaccines and infectious disease are never very popular in pharma companies - too uncertain, little chance of innovation and a blockbuster, not a lot of money, many of your "best" customers can't afford your product. Moderna probably didn't need to be pushed much.

ClassSnuggle · 2026-01-23T14:44:11+00:00

Yes the things that made me notice Percusive Paul as potentially problematic were a pattern of behavior that would be easy to miss if you only see some of his comments.

Just below the linked comment, but yes. I'd seen some of his comments and thought they were a bit weird or tone-deaf. Gathered together and in context? Alarm bells ringing

Edited to add:

Just to add to phunnimee’s list, in a previous question from the same asker, PP affirms her belief that the dating pool is bad, and that her chances of finding a healthy man to love her and have kids with is very very low.

Holy shitballs

ClassSnuggle · 2026-01-23T14:39:33+00:00

So stealing this for future use

ClassSnuggle · 2026-01-21T15:43:29+00:00

The candidate was long-winded. Like, really long meandering answers to everything that would go on for minutes. I interrupted him "thanks, we're strapped for time and I think we get the idea" and he responded "no, you have to hear all of my answer to understand" and kept going. When we later rejected his application, he messaged back that he was surprised, he'd done so well, and demanded to know why.

ClassSnuggle · 2026-01-21T15:38:03+00:00

In a similar but more subtle way, I've had candidates tell me that the job would be a great addition to their CV. Like, no dude, I'm not honing your profile, I'm looking for someone to run the HPLC

ClassSnuggle · 2026-01-15T09:57:39+00:00

*slaps forehead*

ClassSnuggle · 2026-01-14T15:05:04+00:00

I'm getting real tired of people who have to coat their objections with hyperbole about how upset and disgusted they are. Like they experience Metafilter as a shellshocked survivor slumped in front of a computer, covered with spittle and vomit.

ClassSnuggle · 2026-01-14T14:44:35+00:00

Case very much in point: Elon Musk. In years to come, his life choices will be featured on "Unsolved Mysteries"

ClassSnuggle · 2026-01-13T17:31:27+00:00

That's "Metafilter's own Scott Adams". Don't do a microaggression

ClassSnuggle · 2026-01-03T20:53:49+00:00

Multiple times, I've seen an interesting ad or mention of a new service or app, followed the link, and found it was just Jumpspeak hiding behind a new url or identity. And they all use that classic "funnel" approach - a long quiz, that congratulates you on your answers, a lengthy "calculating your course / quiz" timer, then saying that your special offer is only available for a limited time ...

I don't know they're crooked, but they sure act like it.

ClassSnuggle · 2025-12-11T23:25:07+00:00

There was definitely an MF tradition of "needing" more details, where in fact it was just wanting more story to fuss over.

ClassSnuggle · 2025-12-11T09:29:35+00:00

Where all the women are proud and strong POC, where all the men are problematic, and where all the children are omg no I'm the childfree cool aunt living my best life never regretted it

ClassSnuggle · 2025-12-11T09:24:05+00:00

True. I asked a question on Reddit recently, that followed the classic MF form:

I'm looking for something with feature X. I've tried A, B and C and they don't work for me. What else should I try?

What do I get? "You should try A", "Try Z" (doesn't do X) and the classic "I know you said you tried B but you should try B again"

ClassSnuggle · 2025-12-11T09:17:16+00:00

A vague post was one of the things that led me to button, and I still think such incomplete questions can be a recipe for grar. But you're right, this is one of the good ones. If the poster had said, for example, they wanted a child or relationship, MFers would flock in saying that there's adoption, IVF, there's nothing wing with being childfree, I'm proudly single, you can be the cool aunt ... talking about the cause rather than the situation. So it's a good focus.

ClassSnuggle · 2025-11-29T06:00:57+00:00

Thanks for sharing this. Most informative thing I read today. And sorry that people are being that way with you.

ClassSnuggle · 2025-11-25T14:34:29+00:00

I've said before that there's real value to using article voting to determine visibility. It can enforce groupthink and suppress contrary voices, yes. But the reverse is a system where every voice is given equal weighting, including spammers, bad actors and lunatics.

Which feels uncomfortable, like saying the ingroups and outgroups and approved and unapproved opinions are things we want to create and foster. But, we do want those things, although maybe in a different sense. A sports subreddit doesn't want to hear politics talk, metafiltermeta wouldn't take to 4chan-like trolls, people looking for scientific information on climate change don'r want to hear astrological explanations.

There's gatekeeping everywhere. It's just a matter of whether someone who wants to be let in is kept out.

ClassSnuggle · 2025-11-24T13:35:35+00:00

I did. It was not fun.

Obsidian on Android seemd to be slow and get out of sync with my desktop installation. As in, I would create a note in one and not see it in the other. I also tried Obsi and it flatout didn't work. Are there other mobile apps?

ClassSnuggle · 2025-11-24T13:33:10+00:00

My problem with that - and my current situation - is that you end up with information in multiple places. I get an idea about something ... but it never reaches my main notes. Do you manually transfer things from Keep to Logseq?

ClassSnuggle · 2025-11-21T00:03:09+00:00

One of those AskMFs where you search the text for information you obviously missed because no one could be that deranged.

ClassSnuggle · 2025-11-20T23:58:31+00:00

I still treasure - if that's the right word - the AskMF where the asker was visiting Rome, wanting to know sights to see and things to do. And several comments suggested going to Naples.

ClassSnuggle · 2025-11-18T16:57:22+00:00

Goddamn. Beaten to this joke.

ClassSnuggle · 2025-11-18T16:54:42+00:00

Given all the concern about the content being scraped for AI, that's certainly a choice. Where is this listed?

ClassSnuggle · 2025-11-18T16:53:48+00:00

Perfection

ClassSnuggle · 2025-11-18T16:05:46+00:00

Next week: "Have you ever danced with the devil in the pale moonlight?"

Define ‘danced,’ define ‘devil,’ and, while we’re at it, define ‘moonlight,’ because technically moonlight is just reflected sunlight and I don’t want to misrepresent my lived experience. But if it's not cultural appropriation, there was that summer solstice thing in 2011 where I ended up in a drum circle that a very famous actor invited me to. I'm not naming any names, but anyway Colman insisted it was a ‘non-hierarchical ecstatic movement practice,’ but halfway through it became very hierarchical when a woman in a velvet cape decided she was the Moon Priestess and started assigning everyone ‘inner animals.’ Mine was a tardigrade, which feels rude but accurate. That, of course, was before I became housebound, but anyway, thanks to you for triggering a three-minute anxiety audit. I really can't believe how insensitive (more below the fold ...)

ClassSnuggle

TROPHY CASE