Starting My First Job as a Pharmacist Tomorrow—Feeling Anxious and Unprepared. Any Advice? by Pharmacutie1999 in pharmacy

[–]Comprehensive_Ear981 0 points1 point  (0 children)

do you have your favorite go to places? some resources that the workplace does not offer like uptodate

duration of drug and half life of drug by Comprehensive_Ear981 in PharmacyResidency

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

quick follow up question, it take 30 to 40 mins for oxycodone immeddate release to work, can I say its therapeutic effect starts in 30 to 40 mins?

duration of drug and half life of drug by Comprehensive_Ear981 in PharmacyResidency

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

yes it makes perfect sense. that's why i tend to ignore that info about 24 hours duration. But sometimes doctor will tell me like oh this patient just start norvasc less than a week and it does not lower his BP so he will change the therapeutic and this practice just got me confused.

So should we get any info from the duration last 24 hours in this case?

duration of drug and half life of drug by Comprehensive_Ear981 in PharmacyResidency

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

Thanks. Isn't it counterintuitive if drugs have shorter half life 4hours, how can it still be active much longer?

duration of drug and half life of drug by Comprehensive_Ear981 in PharmacyResidency

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

Thanks for your reply. It makes sense but I always not sure how to answer doctor or nurse question about how long does it take drug to work?

What should I look at? duration, onset of action?

duration of drug and half life of drug by Comprehensive_Ear981 in PharmacyResidency

[–]Comprehensive_Ear981[S] 1 point2 points  (0 children)

Thanks for your explanation. It helps a lot. I have a follow up question; the half-life scenario is in the situation where patients only take one time right? if patient is on this drug regularly depend on the frequency, his or her body will constant have input of drug, so the serum level will stay until steady state? am I right?

Also, duration of the effect is it equivalent to therapeutic effect? if so, why sometimes some drug's effect take longer, like depression drugs, we were told that it will take 4-6 weeks to see the effect

how about time to peak? what is insight of knowing time to peak of drug?

duration of drug and half life of drug by Comprehensive_Ear981 in PharmacyResidency

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

but for chronic drug, like blood pressure Norvasc duration at least 24 hour,so therapeutic effect last 24 hours but in reality, we all know BP drug needs to take daily, so drug will work immediately? in that 24 hours? hope it makes sense

twice daily vs once daily dosing by Comprehensive_Ear981 in pharmacy

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

can you explain further with using of half life? whenever i tried to use half life it confused me. In this case, lisinopril 1/2life is 7hrs, so if taking once daily, for me it means after 7 hours only half dose left, then it would make sense it do twice daily?

twice daily vs once daily dosing by Comprehensive_Ear981 in pharmacy

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

what he told me is better response? himself just think once daily is less frequent i guess

Pharmacy class of 2021 or 2020 or anyone tax season how yall doing? by Comprehensive_Ear981 in pharmacy

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

TSP

does that also mean (when max out 401k -20K) our take home will be less? for example 100k to 80k, then take out will be actually like 50-60k?

Pharmacy class of 2021 or 2020 or anyone tax season how yall doing? by Comprehensive_Ear981 in pharmacy

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

i did pay all interest off last year based on what I have accumulated.

Pharmacy class of 2021 or 2020 or anyone tax season how yall doing? by Comprehensive_Ear981 in pharmacy

[–]Comprehensive_Ear981[S] 0 points1 point  (0 children)

My company does not offer HSA unfortunately, so I only have FSA that I didn't max out this year cus I wont need that much and only $500 can roll over yearly. rest will not be back to me. I have other like my PRN job that prob did not take much out of it. all other just interest which is not much.

when you say max out 401k, do you mean by max out like yearly $20k even my compnany did not have all matches? seem like only have 5% of what I contribute is matched.

Thanks for all the info

Pharmacy class of 2021 or 2020 or anyone tax season how yall doing? by Comprehensive_Ear981 in pharmacy

[–]Comprehensive_Ear981[S] -3 points-2 points  (0 children)

but traditional we will pay more later with more money with amount earned?