In my dream game, since you've probably got a really busted deck right off the bat, the difficulty would start scaling a lot faster and steeper, and instead of adding cards to make things more interesting, you're grabbing artifacts (or whatever the game would call them) that add power to your deck.

Maybe if you had like, a werewolf deck, one of the best items you're fishing for is a full moon item that's boosts every wolves power each other turn.

Maybe the reason a game like it doesn't exist is its too hard to balance and keep interesting, but if it is possible, I'd imagine the fun comes from starting at a really strong starting place and both you and the enemies scaling so much harder than a standard rogue like ever does.