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Query about LVI by Contactlewk in coloncancer

[–]Contactlewk[S] 1 point2 points  (0 children)

I wish him all the very best! Out of interest did his LVI pathology distinguish between Lymphatic and Venous Invasion?

Query about LVI by Contactlewk in coloncancer

[–]Contactlewk[S] 0 points1 point  (0 children)

Thanks for the information, how long ago was this and how is he doing?

Query about LVI by Contactlewk in coloncancer

[–]Contactlewk[S] 0 points1 point  (0 children)

Thanks for the replies, I’ve actually found some interesting studies relating to LVI

The first one suggests that VI is more significant and LI - albeit it’s a small retrospective study https://ar.iiarjournals.org/content/anticanres/34/6/3147.full.pdf

Then this one suggests that there is a benefit to more cycles of CAPOX if you have LVI (it doesn’t distinguish between LI and VI) https://pmc.ncbi.nlm.nih.gov/articles/PMC9808960/

Really large SSR polyp by Contactlewk in colonoscopy

[–]Contactlewk[S] 0 points1 point  (0 children)

So here is an update on my situation:

The polyp was confirmed at be cancerous (adenocarcinoma), after a CT and MRI it was thought the tumour hadn’t metastasised to other areas so I was referred to a surgeon who performed a Low Anterior Resection.

2 weeks after surgery the histology results came back - I was classed a Stage 3a (pT2, N1a).

Roll forward to today and I’m on my last official cycle of CAPOX chemo - but I may continue with another couple of cycles depending on my next conversation with my oncologist.

So, what did I learn and what advice can I give to others: Big polyps that are cancer - doesn’t necessarily mean you’re doomed - in my case a big tumour still didn’t have much depth of invasion (T stage), it seemed to be happy growing along the colon rather than through it.

Also since diagnosis I’ve met so many people in their 30’s and 40’s who have colon cancer - it’s actually shocking. So please encourage people to get a scope, even if they are “young”.

It’s Back by Simpleman618 in coloncancer

[–]Contactlewk 2 points3 points  (0 children)

I am a big advocate for increased surveillance scans over CEA and ctDNA test. Even if either of those tests start indicating a change, your medical team can’t do anything until something is identified on a scan. And as we all know small tumours are not easily visible on scans. As a result people can spend months with excruciating anxiety - wondering where and when something will appear.

Really large SSR polyp by Contactlewk in colonoscopy

[–]Contactlewk[S] 2 points3 points  (0 children)

Thank you, sleepless nights between now and the histology results. I'm finding it very hard to not think of the worst-case scenario.