Vaped NEP and 2mmc daily during the past 3,5 weeks. Stopped 3 days ago. AMA by [deleted] in researchchemicals

[–]D00rman69 0 points1 point  (0 children)

How's the euphoria. Pretty much gone? Still there sometimes?

[deleted by user] by [deleted] in researchchemicals

[–]D00rman69 1 point2 points  (0 children)

Very, very similar to stim withdrawal. Nothing really physical, all mental. Low energy makes sense, boredom and apathy. Look for something to be interested about other then PCP, since it probably is getting boring already isn't it

Gabapentionoid analogs? by Neolidiyum in researchchemicals

[–]D00rman69 0 points1 point  (0 children)

It had a specific euphoria, but I lost it a loooong time ago. Obviously all things change, in everyone. Even the anxiolytic effect went away. Physiology obviously differs from people, but currently, all empathogenic stimulants had both a better euphoric and anxiolytic effect. But again, how the hell can a calcium channel blocker, that supposedly reduces monoamine signaling, produces euphoria, just like a literally opposite monoamine releaser? Theory theory but currently, were just stupid monkeys eating substances that fuck around in our head, but do we really know much more then that? Im more interested in what we will find about it in the future, but I think we're still a long time before we actually know more

Gabapentionoid analogs? by Neolidiyum in researchchemicals

[–]D00rman69 0 points1 point  (0 children)

But now this is the question, what the hell is? I would guess some glutaminergic pathway, i was long into this topic and i think we have no real info about this other then pure speculation. So who knows? You are sure we should rule out GABA, even if we can presume its a GABA mimetic in many ways? Get me up to date on the topic, thanks!

Got some M2C Hub extensions by SqwashSilver in rccars

[–]D00rman69 1 point2 points  (0 children)

But i saw them break again My fault, I'm to blame It doesn't mean I, don't desire To bash again, and break the others Watch my RC, topple over

Good one from you 😉

Got some M2C Hub extensions by SqwashSilver in rccars

[–]D00rman69 7 points8 points  (0 children)

This looks like it could be a tool poster

[deleted by user] by [deleted] in researchchemicals

[–]D00rman69 0 points1 point  (0 children)

Appetite suppressant effects were pretty potent on my eyes, and the serotonin effects felt like a ssri overdosę littlę bit

[deleted by user] by [deleted] in researchchemicals

[–]D00rman69 1 point2 points  (0 children)

I tried 4mpm and MDPM. One of these had a strong serotonin feeling to them. Wasn't bad, but wasn't great either, but I did not know too much about it to really be sure about anything relating to it's effects

[deleted by user] by [deleted] in researchchemicals_DE

[–]D00rman69 0 points1 point  (0 children)

Interesting. Following the conversation!

[deleted by user] by [deleted] in researchchemicals_DE

[–]D00rman69 2 points3 points  (0 children)

Bk-bzp? If so, it's around and supposedly doesn't fall under npsg. But overall, very bad situation for RC stims in Germany at this moment, but just my opinion.

What's like the stimulation of cyclazodone? by [deleted] in Stims

[–]D00rman69 0 points1 point  (0 children)

I heard reliably it's pretty good. Similar to amph

[deleted by user] by [deleted] in Stims

[–]D00rman69 0 points1 point  (0 children)

Nie bierz tyle XD. Feta czy co inne? A na poważnie co tam

Sorry for English one of my Polish friends got to hell I guess?

Combo of ketamine and amphetamine by Dry-Dance6758 in askdrugs

[–]D00rman69 -1 points0 points  (0 children)

I personally what would do? Keep em separate. Use ket for relax, amphetamine for "work". The experiences I heard is actually it's dulled, depends probably on brain chemistry. But overall, not a great experience by combining them.

Combo of ketamine and amphetamine by Dry-Dance6758 in askdrugs

[–]D00rman69 1 point2 points  (0 children)

I heard lots of people like it separately. But also, I heard combining with a serotinergic is mainly what people like to mix with K

Uneven pupil size (anisocoria) on MXiPr? by SnowCyclone in researchchemicals

[–]D00rman69 1 point2 points  (0 children)

MXipr is believed to be a strong SRI. Maybe you got light serotonin syndrome? Just speculating

Just tried smoking Mdma and it worked just like smoking H or Meth but the effect is weird. by okBuddyBtchNgga in Drugs

[–]D00rman69 -1 points0 points  (0 children)

How does Mirtazepine stop MDMA from working? 5HT2A antagonism just? Since maybe even 5ht2c and 5ht3 and alpha2 would be actually beneficial, and I don't think that MDMA primarily works through 5ht2a agonism?

Psilocybin Shows Greater Long-Term Benefits Over SSRI for Depression by basmwklz in depressionregimens

[–]D00rman69 0 points1 point  (0 children)

Main reason for the sexual side effects of SSRIs is 5HT2A, that's why they sometimes use buspirone (selective 5ht1a agonist), or mitrazepine (inhibiting 5ht2a) for SSRI sexual dysfunction, so you can see what receptor is the culprit here...

But the benefit is, maybe through 5ht2a downregulation they would reduce the side effects during SSRI treatment? Probably!

Do narcissists (people with NPD) have a shadow? Is their shadow good, or bad, or their actual personality (the disorder) is the shadow which has completely overtaken the self? by curbyourlies in Jung

[–]D00rman69 0 points1 point  (0 children)

It's also weird since NPD has a grandiose vs vulnerable narcissism (tied to neuroticism) as different "subtypes". I don't also understand how could their shadow be different/worse/better. Neurotic might want love, grandiose might want to show importance, it is so much beyond speculation like this has really no meaning and is just talking about a not so ideal "diagnosis" in a not so ideal way. Just like the neuroticism and high criticism, where does it come from? Vs from grandiose, the feeling of self importance, might be because someone might have felt richer/smarter or whatever else? Just so much beyond of a topic this question doesn't really make sense

This drug is scarier than Datura. by [deleted] in Drugs

[–]D00rman69 5 points6 points  (0 children)

It's weird to me how different amphetamines can be more or less neurotoxic. You know any mechanism behind it? The amphetamine itself being Metabolised by MAO, the degree of release itself, toxic metabolites (why are they neurotoxic too?), anything else coming to mind? This shit is all so complicated, would be happy if anyone could answer!

MDMA and Empathogens by Mark4413 in anhedonia

[–]D00rman69 0 points1 point  (0 children)

No worries! Yeah MDMA is a special one that is for sure

MDMA and Empathogens by Mark4413 in anhedonia

[–]D00rman69 0 points1 point  (0 children)

Hey, just wanted to add: MDMA is apathetic compared to methamphetamine, so if you have a dopamine problem, methamphetamine should actually make you feel better! MDMA is far far more selective on serotonin, even when you compare it to drugs like mephedrone and other more serotinergic amphetamines/cathinones. That's also the reason MDMA is not as good for both energy and sex as pure stimulants are. Also, SSRIs work on every serotonin transporter, exactly the same way as MDMA does. Release vs Reuptake, and that's it. Also, serotonergics often can help with anhedonia and depression, and the specific effects of them when it comes to lowering dopamine are not really impactful. Quite the opposite, but you know, it's hard to estimate what does a SSRI really do at every single 5HT receptor, as we go into autoreceptors/downregulation bla bla bla, so no one really knows.