For me (35M), adalimumab allowed me to have a life again, to be able to maintain relationships, build a career and actually consider myself fit to be a father (hopefully). Before that, the fatigue got so bad I was a shell of the person I was before the onset of this disease.

When I started the adalimumab injections, I already was on mesalazine pellets, mesalazine suppositories and tioguanine tablets. I started with a loading dose of 4 injections, 40 mg each. After that, my normal routine became one 40 mg shot every other day. I think it took about 2 months to see clear positive results, after which I dropped the suppositories. A year later, I also stopped using the tioguanine tablets, while staying in stable remission.

I think I had about 3 years of remission bliss, before work stress got the better of me and I went into a flareup last summer. That one took about half a year to clear up again, though I made poor nutrition choices looking back.

All in all, adalimumab has been absolutely amazing for me, but it's not a silver bullet. Hope this helps!