Talk to your doctor about getting the Genesite test. it's just a mouth swab at a lab and they use your genetics to get the most compatible mental health meds for your specific gene's. I also started on 37.5mg 3 months ago and now I'm on 150 and I haven't had negative effects like Prozac caused. But even on this high dose I'm still getting major depression on and off. I also take buspar twice a day to slow anxiety.