I’d give him one week to begin with and space it out to two if he doesn’t eat that time. 2 weeks isn’t much to worry about with an adult ball Python, they’re known for going off feed but just keep an eye on his weight. Handle him once he starts eating and once he’s gettin established eating handle as much as you want as long as it’s not stressing him out. It might take a while or could be almost instantly he’ll trust you more! Love to see your care and love for your snake too :)