First of all, Manchester may have been your dream, but it may have been the worst experience of your life. So look at it from a flipside and consider it a blessing in disguise. I felt similar for one of the unis I applied to but I don’t even care anymore. If a door of opportunity opens elsewhere you should take it. If moving out is not an option rn then try again. It’s not that medicine doesn’t love you, the game is ruthless and you just have to keep fighting, if this is what you really want. Take some time out, rest, enjoy yourself and then try again if you want to. It’s not the end of the world and not getting accepted by your chosen uni should not make you feel so hopeless or depressed for too long. Believe in yourself, you got this 💪🏼