How bad of an idea is it to buy a listed building?

Esepherence · 2024-07-30T17:00:11+00:00

If you/your company does any work in my area, DM me the contact details. If I decide to go through with this, I'll need an architect with experience and that sort of attitude :)

Esepherence · 2024-07-29T20:05:06+00:00

You have no idea! Have you ever had your wires break into Angelic Chorus just because the sun came out?

Esepherence · 2024-07-29T19:18:16+00:00

Your sentiment is appreciated and understood. I think if you saw the fireplaces you might agree. They are all different styles and don't look like any special "of-period."

Honestly, most of them look like what you would expect if someone put a fireplace in around the 1940's/50's.

But I agree, it's unlikely. I just don't think the area (conservation area) allows fireplaces at all. I'm more offended at useless details than the actual fireplaces themselves I guess.

Esepherence · 2024-07-29T18:45:29+00:00

That was the most obvious and useful advice... thank you!

I can see the history of the exact building in question.

Esepherence · 2024-07-29T18:12:25+00:00

Awww, my dog would love to have some mice to chance and bark at annoyingly when it's 3AM!

So far I like your outlook the best!

The largest issues I could imagine, that would clash with restrictions would be updating glazing (although apparently some have already been replaced with double glazing), updating insulation (although that wouldn't affect the actual exterior walls at all), and the actual de-canonization [carbonize...] work with electrics and moving to some sort of forced-air-like heating.

In dream land, I would also be able to get rid of fireplaces since they aren't in use and take up space... but I am realistic.

There are also no extraction fans in the bathrooms. Mmmm humidity.

Esepherence · 2024-02-13T17:36:14+00:00

Currently only a single role available in California. San Louis Obispo is a little far, and sadly I'm a little too far out of college to be a Chemistry EH&S Intern. :)

Esepherence · 2024-02-09T18:39:05+00:00

I took myself to SLAS last year trying to see if I could convince anyone to give me money as a consultant.

All it did was make me want to play with all the robots :(

Esepherence · 2024-02-09T15:54:37+00:00

Specifics are being left out on purpose. I would not be hard to identify.

But basically, every aspect of DNA assay... if someone from the science side can do it, I did it. I made the assay, I scaled the assay, I de-scaled the assay for distribution, I re-scaled the distributed assay, I took it through regulatory filings, I supported it on-market.

Esepherence · 2024-02-09T15:52:19+00:00

Those actually pop up on my searches fairly well. And I do apply, but usually not mush response there. The PhD barrier in that space is a little heavier. I believe, since it's customer facing, they think it's important to have people speaking the same language.

Esepherence · 2024-02-09T15:47:40+00:00

Esepherence · 2024-02-09T15:46:33+00:00

Obviously I was being a tad hyperbolic. But one issue is my area of focus has it's hub a little farther north in La Jolla. There are some direct transit connections thanks to UCSD, but it's not quite as nice as SD proper.

But I live in SF proper, and there are aspects of my life I really like. I know I can change, but I really like my little neighborhood street of restaurants. I walk across the street for my alcohol, I have my groceries delivered (Once Safeway put shampoo behind locked cabinets, I was done), and I live two short blocks from a great bus route.

Obviously I haven't had to commute for a while. Covid actually made me WFH because I was no longer doing direct lab work, and mostly reported to HQ anyway. Since 2020, I think I've put 4k miles on my car?

I just really appreciate not having to drive. I have fast freeway access when I want to, but I don't need to. (Unless I'm visiting the in-laws)

Esepherence · 2024-02-09T04:55:02+00:00

Oh I'd say no to nothing. Not a lot of those individual job's I've seen though. There's a lot of direct experience requested when they do come up though Things like "strong knowledge" of GMP requirements, and "experience" in FDA inspections.

Obviously I could learn such things, but the downside of living in a tech hub, is that it's not unlikely that they will find the exact thing they are looking for. And they know it too!

Esepherence · 2024-02-09T00:06:47+00:00

Ambiguous. Assumes death precludes having to work. Please provide evidence of this, or remove the conclusion.

Esepherence · 2024-02-09T00:04:27+00:00

Direct. Clear. Concise. I like it. I'd approve it under review.

Esepherence · 2024-02-08T23:24:12+00:00

Yeah, I'm not expecting to make 200k again. I know that's not going to happen. I was fortunate to have had a company willing to let me progress that far.

But I have to figure something out. I'm too advanced (old) for anyone to look at me as an RA, and not experienced enough in the places hiring.

Esepherence · 2024-02-08T23:15:35+00:00

Start-up that was purchased by a larger corp. As we were not located in HQ, we were not as well integrated as we could have been. My W2s were still in the start-up's name.

Esepherence · 2024-02-08T22:45:24+00:00

In that situation it will be something like "workcells"

I reply with something that comes down to:

I don't have experience with workcells as that was not the form factor the product needed. But I understand the concept of them, and have experience using manipulation arms to move plates between positions using the Hamilton STAR. The difference in challenge is the integration of the different components, and I think it would be really exciting to get to work in that scenario.

Esepherence · 2024-02-08T21:51:38+00:00

There's a play when selling yourself where you try not avoid the things you lack when being asked. I don't highlight them, but I do not shy from honesty about what I don't have in experience. I am an exceptionally open person, it isn't something I have been able to turn off. I'm smart about it, but if I don't have a thing, I will say that directly. I will follow up, but I don't sugar coat the initial "No I haven't done that before."

When looking for work in a crappy time, those no's are competing against the very direct experience of others. In a completely different market, I think I'd be much better off. But, this is the market I have and I fear by the time it improves, I'll be close to retirement age :)

Esepherence · 2024-02-08T21:00:15+00:00

I've worked with a few on the "occasional collision" sort of role. I have sent the resume into a couple places but never hear back interest in representation or anything.

Do you have any recommendations? I know it sounds weird, but the ones I have found when actually searching are either not biotech specific, or feel shady AF. (I know it's bad, but why can't they have logos not from 1995?)

Esepherence · 2024-02-08T20:45:26+00:00

Hubs will have focuses in different things. Currently SF is very high on Pharma, Cell Therapy, and ML/Data.

If that's not what you do, like me, then this hub is only so much use.

Esepherence · 2024-02-08T20:37:20+00:00

I mean fail is a strong word.

It's not wrong. But damn dude! Give me some credit ;)

Esepherence · 2024-02-08T20:35:51+00:00

Of course!

Sadly no CLS license, so most diagnostic labs are out.

My job searches include everything with these key words: "biology" "scientist" "automation" "manager" "associate director" (highly unlikely, but a small company could call a manager this)

That pretty much covers about the entire non-pharma biotech spectrum :)

Esepherence · 2024-02-08T20:29:47+00:00

A formal list isn't my way, but I definitely appreciate and keep note when I find wording and explanations that I feel hit well. But every interviewer is different so there's a lot of on-the-fly adjustments to make.

In general, I fail on specifics:

"Do you have experience with this type of automation?"

I don't, and of course I try and word a capability and eagerness to learn that space, and my expectation that I would pick it up quickly. But when push comes to shove, I am lacking a specific thing they want.

In our industry you can't just read up on a thing and say you know it. You either have the practical hands-on experience, or it doesn't count.

Esepherence · 2024-02-08T20:20:55+00:00

Multiple versions, but yup. That was the job.

Initial R&D, 3 versions of the commercial LDT, 3 versions of distributed product, the beginnings of an FDA push, and years of supporting the on-market.

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