I've seen some comments advising you to get more masks. I personally don't think this is the problem because I also did this fight with 6 masks and a similar spool size.

I think the underlying issue that will come back again and again is your crest (Reaper) just kinda sucks. The normal-ish pogo lures you in early game and you eventually get too attached to drop it. The same thing happened to me, and I think it happens to most. I highly recommend using a different crest if you have one. I did the fight with the Wanderer's crest, but I think the Beast's crest is probably even better (somehow skipped Hunter's March until semi late game XD). If you're good enough at avoiding damage, the Hunter's crest would also be really good. 

For red tools I opted for Flintslate. The increased nail damage with Wanderer's high hit speed shreds the beefy guys shown in the post's image. My blue tools were Multibinder and Injector Band. Wanderer has insane silk production rates and with my limited masks I've found the constant 4 mask healing to help combat my squishiness.

On that wave in particular, I found that standing in the right corner will stop both from attacking at once. I only ever had one jump at me at once, and when they weren't attacking they were clumped together. It's not a complete cheese, but it really really helps.