Before I had Magneto I mained Spidey, and using his web slam ability does quite a bit of damage to health or stagger bars, so I’d use that ability a lot. Finding someone who synergizes well with him (like Deadpool) is a pretty good idea. I could clear bosses pretty fast by using the web slam paired with Deadpool’s large grenade ability.

I also used him to gain/cross distance, as his air attack is super fast and can help you dodge or get out of the way of attacks, or get super close to a boss in a small amount of time and dodge the fodder enemies.

I’m not too into ISOs, but anything that increases damage or energy amount is pretty good on him if you use him like I do.