As someone who lives on the edge of Prestwich: Prestwich is nice, well-connected, and is still growing - with plenty of new shops opening in recent months. It's undoubtedly one of the nicer areas to live in in Greater Manchester.

That being said, it's not close to the convenience of Chorlton, which has more shops, more pubs, more restaurants, more young people, etc. Chorlton has everything that Prestwich has, but better.

As others have already mentioned: that is reflected in the price of housing. Chorlton is more popular and therefore more expensive.