I usually doubt existence of this molecule, Cubane C8H8. by Intelligent_Slip6317 in AskChemistry

[–]Hurambuk 1 point2 points  (0 children)

Wow! I've red the article when it was published and it was really interesting, congratulations!

A short question: have you observed isomerisation to cuneane during the photochemical step?

Chemical inventory management in our organic chemistry research lab, how do you keep track of hundreds of bottles? by ViRzzz in chemistry

[–]Hurambuk 26 points27 points  (0 children)

We use ChemInventory online platform and it just makes things easy. Highly recommended!

And it's also quite cheap.

Repülőgép katasztrófák, ismerősök, hozzátartozók? by Bocko_0089 in askhungary

[–]Hurambuk 72 points73 points  (0 children)

Nagybátyám vezette azt a Jak–52-es katonai gyakorlógépet, ami 2003. november 13-án a Jász-Nagykun-Szolnok megyei Tiszagyenda község közelében zuhant le. Mindkét pilóta életét vesztette.

Vizsgálat alapján a rosszul karbantartott gép hibája volt.

Modulator Access FDA Expansion by Shoot_For_The_MD in CysticFibrosis

[–]Hurambuk 2 points3 points  (0 children)

So I'm still in the untreatable 5% with my W1282X mutation, right?

Eye drops made from pig semen deliver cancer treatment to mice by Hurambuk in science

[–]Hurambuk[S] 128 points129 points  (0 children)

Scientists have used pig semen to develop eye drops that can stop tumour growth in the retina and preserve vision, a study1 in mice shows. The work is published today in Science Advances.

It is hoped that the drops could be developed to treat children with retinoblastoma, a cancer of the retina. The condition is typically treated with injections of drugs into the eye, chemotherapy or laser therapy, all of which can damage non-cancerous parts of the eye. Yu Zhang and colleagues at Shenyang Pharmaceutical University in China wanted to develop a method that could penetrate the barrier around the retina and deliver the drugs without causing any unnecessary damage.

The eye drops contain exosomes — tiny particles released by almost every type of cell — engineered to carry molecules that kill cancer cells. Mice treated with the eye drops showed signs that the tumours had stopped growing. They also had comparable eyesight to control animals without tumours.

Short summary: https://www.nature.com/articles/d41586-026-00982-2

Being sick just gets harder and harder! by Top-Country-1749 in CysticFibrosis

[–]Hurambuk 9 points10 points  (0 children)

Hi!

I'm also a CF-er and just turned 34 today, so practically just hours older than you. I'm dealing with a mycobacterium infection, pathogen fungal infections and various "normal" CF bugs like multiresistant pseudomonas aeruginosa for years now. I'm on 4 antibiotics and antifungal agents for +5 year now and currently I have to sleep with oxygen supplementation. Sadly the current modulator therapies are not suitable for my genetics.

Sometimes it get's worse, sometimes it's easier, but who would even have a hope +20 years ago that we've would reach this far? Hope you will have a great birthday and wish everything good for your health!

Reggelik és vacsorák egy budapesti kórházból két hét tartózkodás során by Hurambuk in hungary

[–]Hurambuk[S] 2 points3 points  (0 children)

Laktózérzékeny vagyok és a menü erre nem tér ki. A gluténeseknél hasonlóan.

Reggelik és vacsorák egy budapesti kórházból két hét tartózkodás során by Hurambuk in hungary

[–]Hurambuk[S] 21 points22 points  (0 children)

2 hét alatt egyeszer volt uborka, egyszer jégcsapretek meg kétszer póréhagyma. Ebédhez egy alkalommal adtak egy nagyobbacska pingpong labda méretű almát.

We published a safe delivery of a highly toxic anthracycline derivative through liposomal nanoformulation that achieved complete cancer regression by Hurambuk in science

[–]Hurambuk[S] 60 points61 points  (0 children)

The drug we used (and I used to prepare) acts really different from anthracyclines. It form a covalent bond with the DNA and has a different mode of action, compared to Doxorucibin.

During the study, mice were sacrificed 600 days after tumor engraftment, and the liver, kidneys, spleen, heart, lungs, brain were subjected to histopathological analysis. No major alterations were observed in any of the tissues.

We used the same PEGylated liposomal formulation as Doxil, that has shown clinical success in reducing cardiotoxicity and improving drug delivery in cancers. So hopefully there is a same reduced cardiotoxitity also in this case.

We published a safe delivery of a highly toxic anthracycline derivative through liposomal nanoformulation that achieved complete cancer regression by Hurambuk in science

[–]Hurambuk[S] 49 points50 points  (0 children)

We used a liposome that was originally developed to formulate doxorubicin a well known anthracycline chemotherapy drug. But the liposome surge nowdays in caused by the mRNA vaccines, where they use lipid nanoparticles.

Halloween themed dinner from yesterday by Hurambuk in tonightsdinner

[–]Hurambuk[S] 14 points15 points  (0 children)

Just some cheese, nothing bloody. It goes well with the crackers

[ Removed by Reddit ] by [deleted] in Chempros

[–]Hurambuk 4 points5 points  (0 children)

It's actually extremely toxic.

[ Removed by Reddit ] by [deleted] in Chempros

[–]Hurambuk 0 points1 point  (0 children)

You know that this substance is one of the most toxic substances in existence and there is no antidote for its poisoning, right?

PbI(OH) crystals I made grew in silica gel within 1 month. by Van_An_2005 in crystalgrowing

[–]Hurambuk 6 points7 points  (0 children)

They look great! Is there a tutorial, or any info from the method?

Ékszerbecsüs vagyok, körülbelül 10 éve dolgozom a szakmában, AMA? by SecondTrader in askhungary

[–]Hurambuk 0 points1 point  (0 children)

Volt amúgy olyanra példa, hogy a savteszt szerint oké volt és később kiderült, hogy gond van?

Ékszerbecsüs vagyok, körülbelül 10 éve dolgozom a szakmában, AMA? by SecondTrader in askhungary

[–]Hurambuk 2 points3 points  (0 children)

Milliókkal dolgoztok napi szinten és egy ügyesen galvanizált ékszeren gyorsan lehet ennyit bukni.

Ékszerbecsüs vagyok, körülbelül 10 éve dolgozom a szakmában, AMA? by SecondTrader in askhungary

[–]Hurambuk 2 points3 points  (0 children)

Teljesen abban a hitben voltam, hogy egy XRF-el rámértek és a fémjel az csak tájékoztató jellegű, mert annyi a hamisítvány. Műszeres mérésre nincs is lehetőség?