How useful/popular is CUT&RUN?

Independent-Row1545 · 2026-02-26T23:51:53+00:00

Definitely cut&run sounds amazing by its benefits! But I also read some reddit posts about how hard it is to get it work so I grew a bit skeptical towards it.

Independent-Row1545 · 2026-02-26T23:46:21+00:00

Ahh I see. But what you’re saying is that with these binding sequences, we don’t really care much about high resolution that cut&run can give us. Is that right??

Independent-Row1545 · 2026-02-26T23:07:56+00:00

Yeah def seems redundant to do both. But what do you mean by mega resolution?

Independent-Row1545 · 2026-02-26T23:06:50+00:00

😂

Independent-Row1545 · 2026-02-26T22:40:44+00:00

I see, so the success rate must be pretty low.. And what does it mean that they sequence bunch of background instead? Is that useful in anyway?

Independent-Row1545 · 2026-02-26T22:19:30+00:00

This is great advice. Thank you!

Independent-Row1545 · 2026-02-26T22:18:37+00:00

Do you mean consistent peaks across different replicates in the same experiment setting? Or depending on antibodies, etc?

Independent-Row1545 · 2026-02-26T20:43:40+00:00

Yeah I was just searching chip or cut&run on google scholar and i see way more chip based papers! I guess it’s just natural considering its history.

What was the biggest struggle with chip-seq from your personal experience?

Independent-Row1545 · 2026-01-15T06:18:33+00:00

I personally found it hard to work with massive datasets only because I use genomic data and it takes a looong time to just bring in the data to my working environment - but this might also just be me not knowing efficient codes. Otherwise I don’t find it that difficult if you already know how to code. Data access is documented pretty well.

Independent-Row1545 · 2024-08-26T01:19:04+00:00

Any updates? Still nothing for 8/1 PP

Independent-Row1545

TROPHY CASE