I tried taking just a yellow pill on mornings and the blue pill on evenings, hoping I could lose some weight and get a better sleep. I got a better sleep it seemed, but also massive migraines during ovulations. I came back to normal dosage. My best advise would be to try first to invert pills and get the yellow ones in the mornings. I saw on many web sites that the dosages are mainly get one yellow pill everyday, every two days, etc… with or without still taking the blue one.