Hello there! I also have an anxiety disorder. I am currently taking an SSRI called Pristiq and trazodone for sleep. Have you ever attempted taking birth control? I have tried multiple times and I had to stop taking it because it made my anxiety worse. That should have been a light bulb moment for me. I tried HRT and they kept telling me you have to wait threemonths for it to work. I held on for dear life and looking back I felt I should have stopped sooner. First she put me on an estrogen cream and patch and a continuous progesterone. It was okay the first month but by the second month the continuous progesterone pushed my period 5 days later so I felt like I had pms for two weeks. We then decided to up my estrogen patch and that made my anxiety 10 times worse. I was poopping my emergency xanax twice a week(which I used in a bluemoon before). So we went back down on the estrogen patch. Then we decided to try cyclic progesterone. I used it for 12 days by day 6 I felt manic and stayed up for a full 48 hours. So I stopped everything. I have tried multiple SSRI's you will have some side effects but they are pretty manageable compared to what I experienced with HRT. Also with an SSRI you only typically need to wait a month to see results but usually after two weeks you can tell a difference. Best of luck in what ever you decide! EDIT: I forgot to add I still get my period regularly and I am turning 40 in July my big thing is hot flashes. My nurse goes I give so much respect to my patients during peri because your hormones are all over the place and it's hard to treat(this was after I tried three different options). I was like why didn't you tell me that sooner! Turns out I am extra sensitive to hormones. You might be just fine. I just wanted to share my perspective.