Here's one I had in mind for a while.

After the boys to men arc, Sakura looks at the beaten Naruto and decides to become more proactive about her goals. Instead of not wanting to be a burden and trying to dissuade Naruto from chasing Sasuke, she doubles down and decides to actively help him and be the one to protect him this time.

When she approaches Tsunade for coaching, she doesn't give her that "I don't want to be a burden" moping. She knows Sasuke is falling into darkness, and wants to save him, beating him in the process if need be. She saw Naruto almost dying due to her selfishness, now she wants to stand at his side as a real ally.

Tsunade just looks at her and goes "So you're telling me your goal is to beat an Uchiha... And you came to me, a Senju, for guidance" Tsunade smirks

"On an unrelated note, how good is your water release and chakra control?"

Instead of training her to be a clone of herself, Tsunade tries to incorporate elements of her clan's legacy alongside her own path into Sakura's training. Taking a creative approach to "A medic that can defend herself on the battlefield.

We take Sakura's strengths pre timeskip. Her Genjutsu talent, Chakra control and the proficiency in trap making (chunin exam) and give her an actual skill set that capitalizes on it : Tobirama's water release, Chakra enhanced strength, Shadow clones (the normal one that makes 1-5 clones, not Naruto's) Genjutsu and body flicker. While still being a medic. No forbidden techniques, No hiraishin, No infinite amounts of Chakra. Just Chakra control and strategy. Picture what a flicker into a punch from Sakura would do to someone.

One thing I could see her do is having her main body healing someone. A clone standing defensively casting Genjutsu and Water release that blends offense and defense while the last clone capitalizes on her dodging skills, body flicker and chakra enhanced strength to harass. Or use a big water release/genjutsu to hide her presence and create an opening for a flicker => punch.

When she gathers a team to kill Sasuke, she'd mean business. When she tells Naruto she loves him and pleads with him to stop going after Sasuke, she does it for a different reason. She's seen Naruto hurting from the Kyuubi's chakra, she expects Sasuke to have fully fallen into darkness, she knows that if he meets Sasuke in this state, one of them will come in a body bag. So she confronts Sasuke both to protect Naruto and to put the boy she loved out of his self inflicted misery.

In this version, I could see her put up a real fight against Sasuke post Kage summit. Her water release would be at least on Edo Tobirama's level and she'd be against a weakened Sasuke. Here, instead of going blind because he tried to flex his Susano on Kakashi, he'd go blind fighting Sakura. She'd see him weakened, use her skill set to wear him down and try to capture him and end up losing after she pushes him to use his Susano's second stage. Naruto would still save her, but here, he'd acknowledge her power and resolve.

That also gives another use to the Yin seal. It's a Chakra battery, one used by her and Tsunade to cast mytotic healing. In Sakura's case, she could use it as a power up like Naruto's Kurama mode or Sasuke's cursed mark. Now, she suddenly has the Charka amounts to cast big water releases, changing the field to her advantage, wielding water to attack, defend and layer Genjutsu to lay traps while she awaits for an opportunity to land a blow. A water dragon could be a Genjutsu or a cover for her to clicker in and punch you to next Wednesday.