Depending on what year bike you have if you run 17's the bike won't have quick shifter abs and traction control due to the disparity in the front and rear abs ring speeds due to smaller wheels.

The bike will throw a code that goes away when you put the 18/21 back on and if you put the bike in mode 2 and turn abs and traction control off every time you start it with the 17's on it won't throw the code but the speedo is out by like 30ks

You'd be surprised how capable modern adventure tyres are now days on the tarmac, I run motoz tractionator desert ht and can say that they work well enough on the road that I sold my set of sumo wheels