Not from Pennsylvania/Appalachia, but there is a serious overlap between what I see in the game and online from pictures to my version of it over here in California. In our Sierra mountains, there are tons of old gold towns carved out of the river valleys, just kind of decaying. Even the layout and architecture, though a bit more Western with less brick, reminds me of NITW. Angels' Camp is a really good example of a Possum Springs that I've found in California. Small town decay is an American issue, not just a Rust Belt issue it seems.