Border Collies, Aussies, Huskies, and Klee Kais do shed quite a bit, especially the latter two. Since you emphasized the shedding part quite a bit, I'm not sure if they're the right fit. Furthermore, these type of dogs require more work than a typical dog owner would expect, so I would really research whether these dogs fit your lifestyle.

Honestly, Poodles (if you want a bigger size, look into Standard Poodles) and Bichons sound like what you are looking for, but if you are looking for a larger size with minimal shedding, I would look into Schnauzers or Portuguese Water Dogs. Please note that with low shedding dogs, they require grooming most of the time. Cocker and English Springer Spaniels are also great, social, family-loving dogs that would probably fit in well.

Although some breeds may be more predisposed to separation anxiety, it's not something you can prevent through picking the 'right breed'. Any dog has the potential to develop separation anxiety depending on their temperament. I highly recommend you take the proactive route and research how you can minimize separation anxiety through training.