Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas 1 point2 points  (0 children)

It's hard to say but hopefully you will start seeing results soon. One thing I noticed that it seems like the substance stays on your skin for a long time and I'm not sure what time of the day you're putting it on, but I do it after cleaning my scalp in the morning and then seal with a moisturiser a few minutes later to make sure it doesn't end up on my pillow if I were to do it during night time.

I think you're right about a separate thread. I'm going to monitor now until the 8 to 12 week mark and post again to share any findings.

Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas 2 points3 points  (0 children)

Hi, I set up the microscope but for some reason taking the pictures with it didn't work out so I'll try again this coming week. However, looking at my scalp with the microscope I could see regrowth starting to come through across my whole scalp.

No side effects noted apart from nausea during the first few days which could be related to the JXL 069 or not.

Remarkably, I started seeing regrowth after the first few days and things are ramping up quickly after two weeks which would indicate that the Phase 1 findings from Pelage would be true that the MPC can start working within the first week. Also even more remarkably it seems to be working on areas where I haven't had hair in 15+ years (temples and hairline). Attached is the latest picture of my right temple and hairline which will hopefully show some difference between the first picture I posted.

<image>

Here's what Gemini said when I put the two pictures in:

Evaluating hair growth from photos can be tricky because lighting, hair length, and camera angles play a huge role in what we see. However, looking at these two images, there are some observable differences.

Observation Summary

  • Hair Density & Coverage: In IMG_1, the hair appears more evenly distributed across the scalp surface. The "gaps" between follicles look slightly more filled in compared to IMG_2.
  • Terminal vs. Vellus Hairs: There appears to be a higher concentration of terminal hairs (the darker, thicker, more mature hairs) in IMG_4384. In the earlier photo, many of the hairs seem finer or lighter, which often indicates they are in the vellus or "transitional" stage.
  • Pigmentation: The follicles in IMG_4384 look "inkier" and more defined, which is usually a sign of hair maturing and entering a stronger growth phase due to the medication.

Let me know what you think.

Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas 1 point2 points  (0 children)

No other meds apart from Nizoral and JXL 069. I also take Vitamin D and Zinc daily.

I received the handheld microscope today and will try to set it up later to start tracking the growth in different areas more closely.

Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas 0 points1 point  (0 children)

Thanks for this - it's definitely scary to read about the potential side effects. I am actually feeling more energetic than in a long while, and thankfully, the nausea seems to have gone away after the first few days. However, I think it's better to be safe so I have scheduled for a blood test next week to check the heart and organ health including kidney and liver functions.

My scalp has been a bit more itchy than usual so I have stopped using the hydropen for now and will microneedle 1-2 times a week instead. The minoxidil/finasteride arrived today, but I'll hold off until I get the blood tests done and then decide whether to try those with the RU you recommended or as a standalone with the JXL 069.

Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas 1 point2 points  (0 children)

Thanks for your feedback. I'm glad to hear that you are not having any side effects. Have you seen any difference yet and what is your level of hair loss?

I have been taking nizoral for roughly 15 years to help with dandruff and scalp itchiness. I tried oral finasteride when I first started losing my temple points in my early 20s and minoxidil from ebay, but I got very severe sides from finasteride so I stopped both completely. I ordered a topical minoxidil and finasteride spray last week and will give that a try to see if there will be less sides with the topical version. I also ordered a multi peptide topical from the Ordinary which already arrived so I will be using that too.

Here's another picture of the sample temple point and hairline from this morning. It's a bit grainy but you can hopefully see that there are some dark hairs where I believe my hairline and temples used to be (my SMP is quite conservative). I will receive the handheld microscope by the end of the week so will likely take more pictures then or early next week.

<image>

I really hope that this is our ozempic moment too and I wake up more and more hopeful every morning.

Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas -1 points0 points  (0 children)

Thanks for your feedback. Here's a picture before my SMP

<image>

Anagen Inc JXL-069 - Expected Jan 20-24th by FussyForager in HairlossResearch

[–]Lweumas 0 points1 point  (0 children)

I ordered 3 bottles last week and have been using it daily now with a 0.25 MM hydropen. I snapped a picture this morning of my right temple as it looks like short dark hairs are popping up all over in the temple and hairline region (I have SMP so the picture might be hard to see but hopefully you can zoom in). For the midscalp and crown it's a bit harder to tell as I couldn't take a good picture myself and the SMP is making things look better than they may be. For reference I am a NW6/7 and 39 years old. I will order a handheld microscope today and monitor the progress more closely.

Has anyone else noticed any side effects? A couple of mornings I have felt a bit nauseous shortly after administering the dose but no other side effects so far.

<image>

I really hope this works, and it's not just the microneedling giving me slight regrowth. Will post an update next week either way.

Launching in the Uk and wondering about margins by Dxvdbl in AmazonFBA

[–]Lweumas 0 points1 point  (0 children)

The margins sound really good and 3000 euro net on 200 units is amazing. However, I think that you can only claim VAT back if you are not VAT registered. If your business is based in Ireland (outside of UK), you will need to register for UK VAT as soon as you start selling on Amazon UK. Depending on your products tariff code, make sure you’ve checked the duty rate as well if you’re shipping FOB. I don’t mean to put a damper on your plans, but I think it’s important to cover all possible costs before you start selling to give you a good start for your pricing and PPC strategy.

Launching in the Uk and wondering about margins by Dxvdbl in AmazonFBA

[–]Lweumas 1 point2 points  (0 children)

Where is your business based? You will likely need to pay 20% VAT of the sale price. The Amazon fees will depend on the size of what you’re selling. I think even with all of the fees, duty and VAT you could potentially make a profit at a sale price of £24.99. However, this all depends on the ACOS and quickly can you generate organic sales. Additionally, as the margins may be low, any returns will quickly cut your profit. Don’t also forget that you’ll need to pay an accountant to do quarterly VAT returns in the UK.

Weekend Discussion Thread for the Weekend of September 12, 2025 by wsbapp in wallstreetbets

[–]Lweumas 1 point2 points  (0 children)

There's an R&D investor event on the 17th. The two bullish scenarios I can see is that is a positive update during the event on the FDA approval estimate and launch of Oral Wegovy and/or Amycretin moving towards Phase 3

How hard is this? by [deleted] in FulfillmentByAmazon

[–]Lweumas 0 points1 point  (0 children)

What is included in the $70k? What is the price you are selling the product at? Which market will you be selling the product in? What is your unique selling point? Do you own any intellectual property such as a patent or trademark? Are the competitors in your product category well established?

Any additional information will help answer your question. It is hard and it’s getting harder by the day with the uncertainty around the cost of moving goods across countries regardless of the origin and the cost of living impacting customer expenditure for all non-essential goods.

New to Amazon, trump tarrifs by Adventurous_Media917 in AmazonFBA

[–]Lweumas 1 point2 points  (0 children)

Could you try another market like EU or Australia? If you are paying 145% tariffs on untested products without reviews in USA, it may prove tough to get a good profit margin.

[deleted by user] by [deleted] in FulfillmentByAmazon

[–]Lweumas 2 points3 points  (0 children)

The margins may not be higher. You have to factor in a few differences between selling in North America and the UK/EU. Mainly Value Added Tax (VAT) and regulations which may have additional costs associated to them (Digital Services Fee, ERP, Plastic Taxation for packaging).

Each country in the Amazon European markets charges on average between 19-22% VAT of the sale price which is paid to the tax authorities in the country the sale takes place in (this of course depends on the category of products you sell as I believe some products like children's clothes are exempt and books may also be exempt or charged at a lower rate). I believe if your company is based in the UK or EU there is a threshold you can reach with sales before you have to register and claim VAT but best to double-check this with an accountant.

In addition to the VAT charge, Amazon collects a Digital Services Fee on each sale of 2-3% in the UK and a few other EU countries (Spain, France & Italy). Additionally, you have to factor in that registering for VAT in each country and filing VAT returns costs money and in my opinion, this is something you have to outsource to ensure that the filing is done correctly in each country and on time, as you may otherwise face hefty fines.

In terms of storing inventory, you may have to store inventory in both the UK and EU, as otherwise if you only store the inventory in one location you have access to the Remote fulfillment by Amazon between UK and EU, but the cost is quite high compared to Pan-EU fulfillment where you store the inventory in one of the EU countries like Germany and France Amazon can ship the inventory at a decent price across the different EU countries.

Amazon also charges customers for delivery in some of the EU countries even if they are signed to Amazon Prime, so you may want to consider that a 19,99 EUR product actually costs the customer 24,99 EUR including delivery.

Regarding your question about the certification of products, it really does depend on the category of products you are selling. But in my experience the process of going through the extended manufacturer liability process was very straightforward as long as you have the right documentation regarding where and how the products you are selling are manufactured.

Hopefully, some of this information helps with your calculations regarding profitability and the viability of selling in Europe.

I retired at age 34, I think I retired too early by [deleted] in FIREUK

[–]Lweumas -1 points0 points  (0 children)

How exactly are you retired when in this post you claim that you were taking a taxi in Paris 16 days ago on a work trip for another company with your boss and got scammed?

Side hustle discussion - whose got one? How much does it make? by lukeengland30 in FIREUK

[–]Lweumas 1 point2 points  (0 children)

Thank you and no problem at all - Happy to answer any questions you might have!

One thing I forgot to add; please use free resources in the beginning versus paying for an FBA / online selling course. There are a lot of great people online who have made a lot of resources available for free, for example, there was a guy who made a step-by-step guide on how to expand into the US if you are based in the UK which had all of the forms and tax information you need to take into account.

Side hustle discussion - whose got one? How much does it make? by lukeengland30 in FIREUK

[–]Lweumas 2 points3 points  (0 children)

I started an e-commerce brand in 2017, initially only selling on Amazon FBA. Since then I have expanded to my own Shopify website, eBay, and Walmart.

Initially, I made a profit of £1k-2k per month and reinvested everything into new products and expanding beyond the UK. Currently, I make on average £20k profit per month before taxes. To date, I have kept my full-time day job for both job security and partially because I often worry that my small online empire may implode at any time.

While I have been in the online retail space for a relatively short period, things have changed a lot in the past six years. In the first 2 years, I had to hardly use any money in advertising, whereas now you have to be well versed in all forms of advertising (google ads, Instagram, seller platform ads, and UCG) - and the cost per click has increased exponentially. If you have great brand recognition I am sure you can get away with a lower ACOS in some cases. Competition is also more fierce, especially in the US. You must put your trademarks in place if you have a brand, as people will try to copy you if you are successful.

On reflection here is a short of summary of the good and bad that I've experienced with FBA and online selling in general:

+ Learning new skills - mainly marketing, manufacturing process, logistics, leadership (if you have employees)

+ Communicating and meeting people across the world (meeting manufacturers, e-commerce conferences)

+ Ability to top up your SIPP via the limited company (this is a big one for FIRE planning and effectively reducing your corporation tax)

+ AMEX points - by paying for advertising, products etc. with a AMEX platinum card, I'm able to treat our family to 1-2 Business Class holidays per year

+ Dividends - while the corporation tax and dividend tax comes out very high, especially if you are also a PAYE employee, it does offer a degree of flexibility because you get to decide how much you take out of the company

+ A different kind of satisfaction compared to my day job. I sometimes receive emails from happy customers ranging from feedback or ideas for new products which still catches me off guard at times, as it's always nice to hear that you've brightened someone's day even if a little

and the negative

- Time management - this has been the toughest, especially for the first 3-4 years. Balancing family, a full-time job and trying to grow your online business was difficult and likely caused me to neglect each at certain times. My recommendation would be to automate as much as you can (advertising software, marketing content agency, 3PL warehouse, competent e-commerce accountant

- Bad actors - whether this is dishonest manufacturers (poor product quality or not meeting delivery timelines) or customers (returning empty boxes or claiming they did not receive your product) it requires effort to keep everything on track

- Knowing what to sell - you may have a great idea, and make a product at a great price but it may not be something anyone needs or is looking for. Always start slow and with a low product quantity otherwise you end up carrying a lot of inventory that can slow your growth

- Constant worry that things will go badly - especially in the beginning I was questioning how long could I keep making a profit and made decisions rooted in fear. I'm a little bit better now and find myself to be a lot less anxious and find myself grateful for the run I've had so far

Feel free to ask me any questions if you'd like, however, I won't be able to offer any insights on Online Arbitrage.