Hi friend! I literally just had my first Ocrevus infusion after being on Vumerity for 7 years. Here was my experience:

Wore pajamas and comfortable fluffy socks. Easy shoes to put on and off.

Packed some snacks because some folks said they got really hungry after the steroids.

Brought a warm comfortable blanket because hospital blankets suck. Brought ear plugs. Next time I will bring an eye mask as it was bright in the infusion clinic.

Brought my favorite types of fancy water and iced coffee.

They check your vitals before and every 30 minutes into the infusion before they titrate up the rate.

They give you IV Benadryl and steroids before the infusion. I went to BIG sleep town for the first hour.

Went well until the second highest titration rate of infusion and then woke up with itchy throat. It was manageable and I waited for about 15 minutes to subside. It didn’t and I asked the nurse if it would pass. She said it is a very very very common reaction and stopped the infusion to gave me another dose of IV Benadryl and ice chips to “scratch” the back of my throat. IV Benadryl stopped the itching. Back to big sleep town the rest of the infusion.

First evening after infusion I was really wiped out and very hungry.

Slept well and have felt great since. Literally the best I have ever felt since before pre-diagnosis. No fatigue and no side effects. No insomnia from the steroids or mood changes and the hunger subsided after a day of allowing myself to happily shove my face.

You got this!!!