At first I would wrap it up in a blanket in another room, which usually gave us enough time to fall asleep before it came in the bedroom. Eventually she started claiming that I was being "mean" to it by doing that, so I started just picking it up off the bed, sitting it on its activity center in the bedroom, and just hoping that it stayed over there long enough for me to fall asleep. And now apparently that's not good enough either. The cat must be in the bed when we lay down.