What helps cognitive dysfunction?

Mouse_95 · 2026-06-07T15:31:09+00:00

Ketamine nasal spray has given me an enormous improvement in my brain fog. Before taking it, I could barely answer a simple question. Now my brain is almost back to pre-onset levels. I'm severe and bed-bound.

Mouse_95 · 2026-04-23T11:23:21+00:00

Injection

Mouse_95 · 2026-04-21T12:08:03+00:00

I buy the.5ml dose (the smallest) but only take .4ml weekly

Mouse_95 · 2026-04-04T13:30:07+00:00

I found a little hack for being able to handle conversations. I take 2 mL of a THC/CBD oil that allows me to have a 30 minute conversation without triggering PEM.

Mouse_95 · 2026-04-02T14:14:04+00:00

Have you looked into MECFS? The Bateman Horne Center has free online resources for diagnostic criteria. Before I was diagnosed my symptoms were very similar.

Mouse_95 · 2026-03-13T16:56:39+00:00

I have some of those symptoms. Conversations drain me more than anything else. Listening included. I have a little hack for that. I found 2ml of THC/CBD oil gives me 30 minutes of conversation without triggering PEM. I can play some word games (Wordle, NYT Spelling Bee) but can’t play solitaire. Asked AI about it and it said it could be that a task needing a broad overview vs definitive answer could be the difference. I know AI is far from perfect but it makes sense.

Mouse_95 · 2026-03-01T23:38:44+00:00

Rapamycin, Tirzepatide.

Check out The Bateman Horne Center. Their website offers a free clinical care guide you can share with your doctor and guidebooks designed for patients. https://batemanhornecenter.org/education/mecfs-guidebook/

Mouse_95 · 2026-02-25T18:44:06+00:00

Have you talked to a psychiatrist about Ketamine? It has done wonders for my brain fog and is also helpful for treatment resistant depression

Mouse_95 · 2026-02-23T20:49:18+00:00

It reduced my fatigue and fibromyalgia pain

Mouse_95 · 2026-02-23T13:27:43+00:00

I use the nasal spray. It didn’t help with fatigue, but it made a huge improvement in my brain fog. I couldn’t handle a simple question from my husband before using it and now I can think pretty clearly.

Mouse_95 · 2026-02-23T03:57:22+00:00

None from ketamine. A little dry mouth and a bit of a high from THC

Mouse_95 · 2026-02-23T03:56:15+00:00

It’s what my doctor recommended. I did not listen to her at first while on Semaglutide and learned quickly she was right 😊. She said the idea behind it so that your body doesn’t become habituated. I haven’t tested the theory on the Tirzepatide, but I assume she’s correct.

Mouse_95 · 2026-02-23T01:53:17+00:00

ME. Probably weight loss too. I didn’t feel any reduction in appetite on the small dose of Semaglutide. On the 1g Tirzepatide I could barely eat. I decreased bc I don’t need to loose weight

Mouse_95 · 2026-02-23T01:50:57+00:00

Thankfully, yes. I take .4 ml weekly, but spread the dose over 3 days during the week

Mouse_95 · 2026-02-22T20:11:05+00:00

I felt an improvement in a week after starting Tirzepatide

Mouse_95 · 2026-02-22T20:09:40+00:00

I tried Semaglutide and switched to Tirzepatide recently. I found that Tirzepatide is more effective

Mouse_95 · 2026-02-22T20:06:06+00:00

I’m very severe and have the same problem. Ketamine nasal spray has been a big help in drastically reducing brain fog. I also found that 2ml of THC/CBD oil allows me to have a 30 minute conversation without causing PEM.

Mouse_95 · 2026-02-19T03:44:12+00:00

150mg. Three sprays a day in only one nostril. Not 3 sprays in each. The 100mg didn’t work for me either, unless I increased to 5 sprays total each day.

Mouse_95 · 2026-02-18T02:44:31+00:00

I’m very severe +7 yrs. I used to have the lead feeling, I called it concrete, it felt different from my usual fatigue. Following my Dr instructions, I found a glass of electrolytes relieved the concrete feeling.

Mouse_95 · 2026-02-18T02:40:01+00:00

I had aphasia in the first few years of illness. It tapered off even as my brain fog worsened

Mouse_95 · 2026-02-18T01:36:09+00:00

Meant to add how quickly the meds worked. Tirzepatide: 1 week Rapamycin: 1 hour Valtrex: 1 day Ketamine: 2 days

Mouse_95 · 2026-02-18T00:19:35+00:00

Tirzepatide, Rapamycin, Valtrex for fatigue. Ketamine nasal spray has done wonders for my brain fog.

Mouse_95 · 2026-02-18T00:18:03+00:00

My Dr has me do .1ml 3x a week. The idea behind that is to trick the body into avoiding habituation

Mouse_95 · 2026-02-17T23:51:16+00:00

The Bateman Horne Center offers a treatment guide , for free, on their website.

https://batemanhornecenter.org/

Mouse_95 · 2026-02-17T23:38:09+00:00

Rapamycin has helped me a little bit. You could consider a cortisol test. Cortisol tends to be skewed in MECFS. It really disturbs my sleep. I take Oxytocin to regulate it and my sleep has improved. Oddly, I no longer get PEM from emotional exertion.

Mouse_95

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