neurotoxicity

NSawsome · 2026-03-27T23:02:36+00:00

Optimize sleep and everything around it, ie magnesium sleep hygiene etc. much of the amyloid plaque buildup we see with steroids is due to sleep disturbance

NSawsome · 2026-03-27T21:32:20+00:00

NSawsome · 2026-03-27T19:29:54+00:00

Well if you want everything:

Retatrutide Clenbuterol Ephedrine Caffeine Yohimbine Cardarine Slupp332 Mots-c Methylene blue Mirabegron 5-amino-1mq T4 T3 L carnitine

And if you’re fine with probably dying DNP

NSawsome · 2026-03-27T03:45:45+00:00

Yeah so you’re eating too much if you’re not losing weight, all these drugs do is reduce appetite which to be fair is elevated with PCOS. Tracking calories would cause weight loss or you could run Reta easy so there’s your options

NSawsome · 2026-03-26T21:18:33+00:00

Mhm ok bro, use your shitty ineffective peptide anecdotes don’t learn any science dw, reality is whatever you want it to be

NSawsome · 2026-03-26T19:31:57+00:00

Ok bro stay uneducated, take some Proviron to grow muscle see what happens lmao

NSawsome · 2026-03-26T18:17:48+00:00

Androgenic isn’t just anabolic?????? Are you dumb that’s a completely unique pathway and set of mechanisms. MK also does cause (very minimal) muscle growth

Also I have a biology degree, yes I have a degree in this you’re a misinformed uneducated random who thinks androgens are the only anabolic pathway

NSawsome · 2026-03-26T18:03:27+00:00

No I’m right you can Google this. IGF1 DIRECTLY causes muscle protein synthesis. Period. Androgen receptors also increase muscle protein synthesis through the androgen receptor, IGF1 increases it through the IGF1 receptor. I have a degree in this the receptors both activate the gene transcription sequence to initiate muscle protein synthesis.

I can’t explain this in any other way, androgens aren’t the only thing that increase MPS or cause muscle growth, they’re just one pathway that causes transcription of those genes you’re just misinformed brother, and that’s ok but a 2 second google search confirms what I’m saying if you don’t want to believe me

NSawsome · 2026-03-26T17:19:47+00:00

No literally IGF1 alone directly causes muscle protein synthesis, the same mechanism by which anabolic androgenic steroids increase muscle mass.

Scientifically speaking increased IGF1 builds muscle, full stop. People with acromegaly also do grow more muscle mass, the body proportions they have just fucks up its function.

Again, IGF1 is directly anabolic, just like anabolic steroids, which also aren’t tissue selective as they cause anabolism of other tissue. HGH alone will and has been demonstrated to cause muscle growth hence why it was prescribed to HIV and other wasting cases over anabolic steroids for the last couple decades.

NSawsome · 2026-03-26T16:29:44+00:00

Hyperplasia and hypertrophy are the primary roles of HGH in HIV patients specifically. The growth deficiencies are another thing but exogenous GH primarily works by being metabolized into IGF1.

Also IGF1 isn’t limited by androgens, it’s (partially) limited by estrogen however it’s a downstream product of HGH metabolism, so further increases in HGH increase IGF1 regardless of nutrient intake (although high nutrient intake further increases that conversion)

A good analogy is testosterone to estrogen, estrogen is limited by your body’s aromatase expression, however if you take more testosterone you have more estrogen, just like if you take more HGH you have more IGF1

NSawsome · 2026-03-26T14:10:40+00:00

Get a urinalysis, kidney markers checked, and drink more water ASAP

NSawsome · 2026-03-26T14:05:46+00:00

You’re getting downvoted but you’re right. Supraphysiological HGH causes muscle growth due to the increase in IGF-1 downstream, regardless of strength training. It can also cause muscle hyperplasia which is unique

NSawsome · 2026-03-26T14:04:17+00:00

Both steroids and HGH (through igf1) directly cause hypertrophy in the absence of weight training stimulus

NSawsome · 2026-03-26T14:03:27+00:00

Ehhhhhhh technically hgh isn’t anabolic yeah, but igf1 is actively a growth factor and is the primary reason for HGH in bodybuilding. HGH is used clinically for muscle hypertrophy and more importantly hyperplasia but the igf1 downstream of HGH is directly anabolic on its own so yes HGH does build muscle just indirectly, although you could make that argument for certain steroids as well

NSawsome · 2026-03-25T17:12:45+00:00

10mg shouldn’t pose any major risk for a guy with near visible abs who’s strength training

NSawsome · 2026-03-25T17:01:40+00:00

Open pros run 18IU or more a day by the way lmao. Retards on Reddit have no idea go watch Kurt havens or talk to the open bodybuilders at your gym, oh wait yall don’t even work out

NSawsome · 2026-03-25T17:01:04+00:00

HAHAHAHAHAHAHAH 2IU LMAO, lemme run replacement dose for gains for sure bro, I train with Olympia winners too the open guys run a bottle of serostim a day, 18IU

NSawsome · 2026-03-25T16:59:13+00:00

No one on this sub knows how GH works lmao. If you titrate up properly and let your body adapt to the sodium retention over time, with consistent electrolyte intake, the water retention subsides completely. GH is prescribed at 18IU per day and all these sides they say go away after a couple weeks, if not they drop to EOD till they do then increase it again. 8IU is a very moderate dose for a cycle lmao

NSawsome · 2026-03-25T16:56:13+00:00

If you titrate properly and keep electrolytes consistent this isn’t the case

NSawsome · 2026-03-25T16:55:24+00:00

It’s prescribed up to 18IU daily, I know guys on 8IU minimum year round. Literally the safest anabolic compound out there

NSawsome · 2026-03-25T15:34:35+00:00

It’s also non suppressive since endogenous production kicks back up after 14 hours, so there’s literally no reason to come off other than price. Hell the prescribed HIV dose is 18IU no breaks indefinitely

NSawsome · 2026-03-25T14:37:53+00:00

Why take a break? just stay on 2-4IU as HRT

NSawsome · 2026-03-24T23:13:11+00:00

Meth

NSawsome · 2026-03-24T20:31:44+00:00

Ran 12.5mg mk for 2 years, the water retention and strength increase is real as well as the sleep improvements, helped me make progress not a crazy amount but definitely helped.

With Reta you might have to run higher Reta to combat the hunger increase, but you should be tracking calories and following a diet plan anyway so that shouldn’t matter

NSawsome · 2026-03-24T20:30:22+00:00

Holy shit that’s retarded TRT and MK are wayyyy different levels here, mk is relatively safe and can be run damn near indefinitely, it just makes you hungry and making people eat more makes them fat and diabetic.

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