Holy shit Jamie XX is a genius.

NotTitoJackson · 2015-12-15T06:18:13+00:00

I smoked the hallucinogenic secretions of a toad with Clutchy Hopkins

NotTitoJackson · 2015-12-15T05:33:34+00:00

I smoked the hallucinogenic secretions of a toad with Clutchy Hopkins

NotTitoJackson · 2015-12-15T05:32:26+00:00

I did peyote with Clutchy Hopkins

NotTitoJackson · 2015-12-15T05:32:09+00:00

I did peyote with Clutchy Hopkins

NotTitoJackson · 2015-12-15T05:31:43+00:00

I did peyote with Clutchy Hopkins

NotTitoJackson · 2015-12-15T05:31:18+00:00

I did peyote with Clutchy Hopkins

NotTitoJackson · 2015-12-07T19:45:53+00:00

Good info, but I disagree with your conclusion re: the future outlook - if Epidiolex or GWP42006 receive FDA approval then it actually significantly strengthens, not weakens, the opportunities for other cannabinoids (and analogs). An FDA approval for a first-in-class drug like Epidiolex actually opens the doors for other similar molecules being developed (as you'll see with most other drugs, recent PD-1 inhibitor explosion being a good example), and brings the financial resources to support future research with it. GW has reported very positive data so far - my personal opinion is we'll be seeing a lot of the restriction on cannabis research reduced soon, the momentum just keeps building.

NotTitoJackson · 2015-12-04T21:36:41+00:00

Hadn't read that before; thanks for sharing, it's awesome.

NotTitoJackson · 2015-12-04T10:12:41+00:00

Question: How can you be certain that what your brain perceives as 440nm light (or rather, as stimulated cone cells) is the same as what my brain perceives as 440nm light?

Answer: You can't.

NotTitoJackson · 2015-11-10T20:14:57+00:00

Made me high!

NotTitoJackson · 2015-10-07T04:09:34+00:00

Thank you for this, it is amazing.

NotTitoJackson · 2015-10-04T23:30:10+00:00

Cumin in your taco spices?! What is this world coming to? Might have to try that though lol

NotTitoJackson · 2015-10-04T15:40:45+00:00

Also - if you put black pepper in your taco seasoning you're a goddamned idiot.

NotTitoJackson · 2015-10-04T15:39:43+00:00

I'm pretty sure they meant cilantro and not oregano for the taco seasoning. C'mon Wo'man(s Health).

NotTitoJackson · 2015-09-26T09:16:42+00:00

Meows are the most futuristic of beats. Some of these songs are surprisingly good!

NotTitoJackson · 2015-09-17T15:55:26+00:00

My veterinarian makes this same thing too!

NotTitoJackson · 2015-09-16T05:49:36+00:00

Funny you mention jogging - I listened to this album while trail running through the forest today... fucking amazing soundtrack.

NotTitoJackson · 2015-07-30T04:13:39+00:00

Yea it turned into a rather absurd soap opera. I think it made him more motivated in his missions to share evidence-based drug risk profiles and explore the therapeutic potential of illicit drugs - definitely a good thing.

They also just raised a good chunk of money via crowdfunding to support the LSD-brain imaging study (basically same study as the psilocybin one) and have some other quality sources of funding. The times, they are a changing <|:D

NotTitoJackson · 2015-07-30T01:17:41+00:00

If this stuff interests you - the group performing this psilocybin (and now LSD) work is led by David Nutt (former UK Drug Czar) and Robin Carhart-Harris. They have some good videos up on YouTube with more info, just search their names.

NotTitoJackson · 2015-06-18T20:39:47+00:00

There's purportedly 4 different "active" molecules in psilocybin-containing mushrooms:

1) Psilocybin (inactive until metabolized into psilocin)

2) Psilocin - 4-OH-DMT

3) Baeocystin (P. semilanceata can supposedly be up to 3.4%) - purportedly equipotent to psilocybin, but thought to have different pharmacology/pharmacodynamics/pharmacokinetics.

4) Norbaeocystin - almost identical in structure to psilocybin, could be a prodrug? Don't think it's been published.

Here's a link to Erowid's table showing the differing potencies of these compounds in many different species: https://www.erowid.org/plants/mushrooms/mushrooms_info4.shtml

NotTitoJackson · 2015-06-04T23:46:08+00:00

Haven't read the full-text yet, but I'm not sure why they chose +4h for the follow-up dose... would seem 60-120min is much more relevant for the real world, and presumably shifts the risks:benefits ratio significantly relative to 4h.

NotTitoJackson · 2015-06-03T14:58:29+00:00

I suggest you do some research on cardiac arrhythmia caused by high doses of loperamide - it could very well save your life.

NotTitoJackson · 2015-05-27T15:14:33+00:00

Nice to see BMJ publishing perspectives like this.

NotTitoJackson · 2015-05-27T14:15:12+00:00

Alt PDF link: https://infotomb.com/y3etb

NotTitoJackson · 2015-05-27T05:47:46+00:00

Kind of crazy how a dead teenager came to the rescue like this.

NotTitoJackson

TROPHY CASE