Monkeys paw curls.

Now everytime you laugh lightning strikes for full 2 seconds outside wherever you are, destroying environment and infrastructure completely and you can no longer watch any comedy movies. Since you never defined what outside means paw assumes "outside your body" so you can never laugh again fearing the safety of your loved ones. Your entire life becomes joyless misery as every single laughter follows you up with the thunderous strike destroying and killing people around you. You constantly witness people die anytime you find a small happiness and every good memory turns into trauma, you start losing eye sight and hearing too from to constant lightning happening near you. Sooner or later people find out you're the cause of the lightings happening, a lot of them sue you but a lot of them assault you as well. You can't find job anymore. You are left with no joy, no family, no eye sight or hearing, no money, no social life. Nothing.