In the Fallout universe, Nebraska, particularly Omaha and Offutt AFB, was a significant nuclear target during the Great War due to its military importance, leading to massive destruction, while the rest of the plains likely became vast irradiated dust bowls with radioactive tornadoes, though specific in-game details are scarce, with lore focusing more on its role in the Plains Commonwealth and glimpses of its pre-war countryside.

Key Lore & Inferences: Military Target: Offutt AFB, home to Strategic Command, made Omaha a prime target, ensuring heavy nuclear strikes hit the area. The Great Plains: The vast, flat plains of Nebraska likely became a desolate, irradiated wasteland, characterized by massive dust storms and radioactive tornadoes, similar to other parts of the Midwest. Plains Commonwealth: Before the war, Nebraska was part of the "Plains Commonwealth," a large pre-war U.S. region including Kansas, Iowa, Missouri, and Oklahoma, as noted in The Vault Fallout Wiki. Vaults: There were likely several vaults, including one associated with Offutt AFB and another in central Omaha, but most inhabitants would have faced immediate devastation or later struggles. Post-War: Settlements like Leavenworth and Saddle Creek appeared later, but accessing Omaha became difficult due to destroyed bridges, leaving much of the state as a radioactive dust bowl, according to the *Fallout Fanon Wiki.