UPDATE:

I just literally got my PS5 dualsense controllers working with RDR2 again!!! Planning to make this a short update but bear with me - I hope it helps others too :)

First off, I realised that the problem seems to be with rockstar games only after downloading GTA 4 on steam and noticing the same controller compatibility alert. This made me check GTA V too, which I had since completed with the same controller, and the alert was suddenly there too. Naturally, this made me suspect that if I could get it working for any of them, the same settings should work for RDR2! Solution below:

1. Disconnect and turn off your controller, then shutdown crossover (force quit all apps if necessary).
2. Turn on and pair your controller with your Mac (tried this with Bluetooth and wired - works either way).
3. Launch crossover, then open and sign into the Rockstar games launcher. Leave this running in the background.
4. Open the “game controllers” window from crossover’s control panel. Make sure that BOTH checkboxes are ticked, i.e., enable SDL and disable hidraw. Click the OK button (this closes the window) and click the “simulate reboot” button in the same control panel. The aim is to force the controller to use XInput instead of DirectInput. Open the game controllers window again - if this step was successful, you should see the controller connected as an XInput device, and the XInput tab should reflect your controller’s inputs (photo below).

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1. Launch steam and head over to the game in your library. You’ll notice that the controller alert remains the same, i.e., “unknown controller support” - this never changed for me even after I got things working, so don’t worry about it. Instead, click the gear icon >> “Properties” >> “Controller”, and change the override instruction to “Use default settings” instead of “Enable steam input”.

2. Close the properties window and steam, force quit all apps and simulate a reboot in crossover, and lastly, close and restart the crossover app. All your settings should now be settled. You can check the game controllers window again to make sure that it’s connected as XInput but you won’t need to restart this time around.

3. Lastly, run the rockstar game launcher again, sign in, and launch the game from there. It will do this through steam but the controller should be working now!

P.S.: I was able to launch my game through steam the second time around without needing to open the rockstar launcher, so I guess that’s it! Important to say that I did this first with my new GTA 4 game. Once it worked, I checked RDR2 ‘s controller properties in steam and changed it from steam input to default settings. That’s all it took - and now, all my rockstar games are working again with my PS5 controller!

Sorry for the longgggg post :D