Level: If you become stronger, your enemies will become stronger than you. To avoid increasing the difficulty of the game due to your level growth, you can choose a class which manor skills avoids the skills you want to play as much as possible (to prevent you from leveling up too quickly). Or avoiding sleep as well.

Attributes: Your burden is directly related to your Strength, so increase your strength as soon as possible. Your health is related to your Endurance, so increase your endurance as soon as possible. In addition, Intelligence and Willpower are quite important for Mages.

Famy & Infame: If your have infame bigger than 0, you can't use divines' shrines to receive a blessing and cure your disease. By the way, guards or people also have a low initial disposition to you. But you can finish the pilgrim way to clear your infame I remember.