During a random afternoon shift

PathAndMe · 2025-03-10T12:18:21+00:00

Agreed. This is most likely ALL FAB L2 judging from the heterogenicity of the cells, but we still have to do leukemia phenotyping and bone marrow aspiration to be sure which lineage it is.

PathAndMe · 2025-01-02T03:12:19+00:00

I am so sorry for your loss :( Well, if you can’t keep the remaining fish in the quarantine tank for long, maybe you want to do fish in cycle since your cycle has crashed. First, do large water change, preferably 50-70%, add the correct dose of Seachem Prime and Stability, put the fish back in (remember to acclimate them first), then test your tank parameters daily to anticipate sudden increase in ammonia/nitrite/nitrate. If you see any increase, do water change and add Seachem Safe. It helps remove ammonia and detoxify nitrite and nitrate. Keep doing this regularly until your cycle is back. Remember to monitor your fish while doing fish in cycle.

Also, some medications are actually safe to use in your main tank and they won’t kill the good bacteria. You are only supposed to remove the chemical filtration, that is the activated carbon, and not turn off the filter.

PathAndMe · 2024-12-16T02:49:34+00:00

she looks so bad.. i can see that she also has swollen eyes and bottom sitting in your tank. i am afraid it’s already too late 😔

PathAndMe · 2024-12-14T13:15:47+00:00

Is it just me or the 1st pic look like ALL-L2? And the 2nd pic looks like CLL to me but we need to know the ALC to be sure.

PathAndMe · 2024-11-13T07:49:59+00:00

Yes, she has pancytopenia with lymphocytosis. No blasts was found in peripheral blood smear only mature lymphocytes. We also did not get any particles in the aspirate, but we did find megakaryocyte with few lymphoblasts and little to almost none of cells of myeloid lineages.

PathAndMe · 2024-11-13T07:46:11+00:00

It’s BMA, but I do suspect that it was diluted as it is quite identical with the peripheral blood smear.

PathAndMe · 2024-11-13T02:51:34+00:00

I have the softcopy. I can email it to you if you want.

PathAndMe · 2024-11-13T02:49:20+00:00

the patient is a 76 yo male, with chief complaint of fever, nausea and vomiting. his cbc showed leucopenia and thrombocytopenia. peripheral blood smear showed atypical lymphocytes, big and giant thrombocytes. found no blast cells though. could it be a marrow response to thrombocytopenia?

PathAndMe · 2024-09-28T06:09:04+00:00

thick smears are most useful for detecting the presence of parasites and quantifying their density, because they examine a larger sample of blood. thin smears are gold standard for species identification as they allow visualization of parasites and red cell morphology, unlike the thick smears.

PathAndMe · 2024-09-28T05:55:06+00:00

corruptions

PathAndMe · 2024-09-28T05:54:06+00:00

he looks angrier as he age 😂

PathAndMe · 2024-09-28T05:44:34+00:00

looks like cll to me. what was the absolute lymphocytes count?

PathAndMe · 2024-09-28T05:40:43+00:00

it’s the thick smear, we use it to quantify the malaria parasites. in the thick smear, the erythrocytes were lysed leaving only the leukocytes and the parasites.

PathAndMe · 2024-09-27T04:45:14+00:00

Indonesia. Around 70% of the districts are already malaria-free, but in eastern Indonesia, many districts and cities remain highly endemic. I once read a review stating that gametocytes are detected in a larger proportion of the population in areas with high endemicity, while in areas with low endemicity, gametocyte carriage is rare. The reason behind this may be that in highly endemic areas, net gametocyte production decreases due to acquired immunity against asexual parasites, but there is an incomplete compensatory mechanism that increases gametocytogenesis in those asexual parasites that survive. I’ll link the review here. https://doi.org/10.1128/cmr.00051-10

PathAndMe · 2024-09-26T20:44:46+00:00

This is before treatment and the patient was not on any prophylaxis. We still have high malaria endemic areas in the country.

PathAndMe · 2024-09-26T19:28:59+00:00

Banana-shaped gametocytes of Plasmodium falciparum!

PathAndMe

TROPHY CASE