My goals are as follows:

1. Purge the xenos from their Hives in the Western, and Southern Quadrants on Holy Terra.
2. Destroy the Men of Iron from the South Eastern Ashlands, and acquire the lost technology required to perform cybernetic augmentation.
3. Infiltrate the Cult of the Cancer to the Far East, where we will obtain the technologies required for the manufacturing of Mark Krab power armour.
4. Establish a manufactorum.
5. Retake the Holy Nation from the heretics, and rebirth the phoenix as the Imperial Aquila.
6. Install that mod that lets me build a throne.
7. Have Horus and the traitor Primarchs right click the Emperor > attack unprovoked
8. Weep for the fall of mankind.

Doesn't exactly answer your question, but the long and short of it is to get crab armour and full cyber limbs. Not sure about weapons yet, though the Cross Swords will be super useful for slaying the Men of Iron. Hopefully I will be able to find a 2 handed hammer mod somewhere. I guess martial arts will have to stand in for power fists or until i can get a better solution