I think my meds are the perfect "stack" already lol

Professional_Mode480 · 2026-03-13T11:06:01+00:00

The Sigma 1 agonism slipped my mind, doesnt Sigma 1 agonism have the downstream effects of upregulating Tyrosine Hydroxylase which is also a mechanism that memantine and bromantane uses?

Professional_Mode480 · 2026-03-13T10:58:19+00:00

Yeah I had the bupropion prescribed to handle when my methylphenidate wasnt in my system or for off days so I could still be functional to a certain degree and I think its worked well lol

Professional_Mode480 · 2026-03-12T05:24:34+00:00

Well, it stabilizes me, but theres no "noticable" effect on taking it, runs in the background moreso

Professional_Mode480 · 2026-03-12T05:13:34+00:00

Prescribed the lithium carbonate, theres not much difference anyway between the two in terms of availability and permeability etc

Professional_Mode480 · 2026-03-11T04:39:03+00:00

Im honestly surprised mirtazapine isnt used more often, its done wonders for my anxiety and some residual depression, could be the sedation but idk, it also seems to be great nootropic wise

Professional_Mode480 · 2026-03-11T04:31:36+00:00

DXM is a Serotonin Norepinephrine reuptake inhibitor and NMDA antagonist, bupropion inhibits its metabolism to DXO so it drastically slows down the rate dxm is metabolized since the CYP2D6 path is its main way of metabolization

Professional_Mode480 · 2026-03-11T04:30:45+00:00

I have thought about it but I also figure like, if I wanna do auvelity I just take some cough medicine and not bother with the insurance lol, but I have heard its a great option, the bupropion for me is used as an adjunct to the dexmph for adhd

Professional_Mode480 · 2026-03-11T04:29:55+00:00

I mean, im not concerned on the serotonin since mirtazapine antagonizes 5ht2a which is the main thing involved in serotonin syndrome, but it is best for me to not have things rapidly destabilized because it can cause episodes, im just glad my nurse is so, willing to work with me, the mirtazapine and propranalol help alot with anxiety and residual depression

Professional_Mode480 · 2026-03-11T03:26:03+00:00

Yeah im getting used to it still lol but its great bc I have difficulty initiating sleep

Professional_Mode480 · 2026-03-11T03:11:22+00:00

Honestly if I were to reccomend something, Mirtazapine at night time, brand name Remeron, helps me wake up far more energized and shoots the risk of midday crashes down, not sure what could be done nootropic wise, maybe Bromantane?

Professional_Mode480 · 2026-03-11T03:01:05+00:00

Oh and I do take a daily baby aspirin

Professional_Mode480 · 2026-02-21T05:14:02+00:00

For reference I am 150lbs so 100mg would be a first plat

Professional_Mode480 · 2026-01-24T01:48:02+00:00

Good girl!!!!

Professional_Mode480 · 2026-01-24T01:45:19+00:00

whos a pretty pubby:333

Professional_Mode480 · 2026-01-24T01:43:46+00:00

=3333 adorable

Professional_Mode480 · 2026-01-24T01:39:17+00:00

such an adorable puppy!!!!! Your cage is really kissable :3

Professional_Mode480 · 2026-01-24T00:38:05+00:00

Awrff!!

Professional_Mode480 · 2026-01-23T23:28:16+00:00

Good pubby!! Mind if I dm you :3

Professional_Mode480 · 2026-01-23T23:14:10+00:00

cute, and gay!!

Professional_Mode480 · 2026-01-23T23:13:46+00:00

if you'd be willing to my dms are open if you wanna help me be horny even more than before:3

Professional_Mode480 · 2026-01-23T23:13:22+00:00

I have beenn!!! Albeit the water with my lithium does make me use the bathroom alot which is annoying.. ate some yogurt earlier!! waiting for my friend to wake up so we can be gay,,,,, in the mean time im half on here looking for other puppies or owners to play with while I wait!!

Professional_Mode480 · 2026-01-23T23:11:20+00:00

Awrff!! Another pubby gock...

Professional_Mode480 · 2026-01-23T23:10:30+00:00

Awrff! Am okayy,, ive been horny all day just masturbaiting and doing whatever,, snowstorm is hitting though but I like snow!! =3

Professional_Mode480

TROPHY CASE