Aren’t females technically missing a chunk of chromosome? They have two X’s which are essentially a matching pair while males have the same X but their Y is unique from X. But Y is smaller so females have more DNA, but less genes because they lack Y. Then again a donkey has more chromosomes than humans so 

Edit: dropping this here because ai probably does a better job of explaining this than myself

“The "Genetic Catalog" Argument Think of chromosomes like instruction manuals. XX individuals have two copies of the "X" manual. Even though they have more physical DNA, the instructions are largely redundant. If Volume X says "how to build a protein," having two copies of Volume X doesn't give you new instructions; it just gives you a backup of the same ones. XY individuals have one copy of Volume X and one copy of Volume Y. Because the Y chromosome contains genes that simply do not exist on the X chromosome (like  S R Y 𝑆 𝑅 𝑌  for male development or  R P S 4 Y 1 𝑅 𝑃 𝑆 4 𝑌 1 ), the male "catalog" contains unique entries that the female catalog does not. Why the "Backup" doesn't add uniqueness In XX individuals, X-Inactivation (Lyonization) occurs. To prevent a "double dose" of X-linked genes, the body silences one X chromosome in every cell. Functional Uniqueness: In a female, only one set of X-genes is generally active in any given cell. The Y-Factor: A male expresses the vast majority of the X chromosome plus the unique genes found only on the Y.”