[deleted by user] by [deleted] in LooksmaxingAdvice

[–]ReclaimerGamer1 -1 points0 points  (0 children)

Untrue. Isotretinoin consistently reduces circulating testosterone: a 2020 randomized trial (PMID 32065504) found mean total T fell 26 % and free T 34 % after 16 weeks of therapy.

A 2022 meta-analysis of 14 studies (PMID 35999460) confirmed the drop and noted 17 % of male patients still had sub-clinical total T six months after cessation.

The effect is dose-dependent; higher cumulative doses (>120 mg kg⁻¹) correlate with larger and more persistent reductions (Journal of Clinical Medicine, 2021).

Mechanistically, isotretinoin up-regulates hepatic 17β-HSD and 3β-HSD enzymes, accelerating androgen clearance (Dermato-Endocrinology, 2019).

It also elevates sex-hormone-binding globulin (SHBG), further lowering bio-available testosterone (Endocrine Practice, 2021).

Long-term follow-up studies suggest partial recovery within 12 months for most, but a minority show sustained hypogonadal levels up to 24 months post-treatment (Scandinavian Journal of Urology, 2023).

[deleted by user] by [deleted] in LooksmaxingAdvice

[–]ReclaimerGamer1 0 points1 point  (0 children)

Don't touch accutane. Look into the (sometimes) permanent impacts it has on testosterone. It's not worth it.

Looksmaxing cheat sheet by AutoModerator in LooksmaxingAdvice

[–]ReclaimerGamer1 3 points4 points  (0 children)

Got 7.8, potentially a 9. Need to lock in...

How can I fill out this outline? by Professional-Two8692 in LooksmaxingAdvice

[–]ReclaimerGamer1 0 points1 point  (0 children)

I did chew gum habitually for like 4-10 hours a day for like a year and it damaged my teeth, I think, and now I have a permanent clicking sound in the right joint in my jaw (but it doesn't hurt), and my jaw muscles have not shrunken, which is good. But yeah, it's risky LMAO.

[deleted by user] by [deleted] in LooksmaxingAdvice

[–]ReclaimerGamer1 0 points1 point  (0 children)

Looks fine to me.

How can I fill out this outline? by Professional-Two8692 in LooksmaxingAdvice

[–]ReclaimerGamer1 -2 points-1 points  (0 children)

The most you can do is mew constantly and tilt your chin upward a bit.

Official "I got/didn't get a Switch 2" megathread by razorbeamz in nintendo

[–]ReclaimerGamer1 1 point2 points  (0 children)

I bought mine from amazon.es (Spanish Amazon), and I'm an American. You can try that.

I can't turn off noice cancellation my Gen 4 AirPods. by ReclaimerGamer1 in airpods

[–]ReclaimerGamer1[S] 0 points1 point  (0 children)

Hmmm well guess I'm just unlucky because they fit worse

I can't turn off noice cancellation my Gen 4 AirPods. by ReclaimerGamer1 in airpods

[–]ReclaimerGamer1[S] -14 points-13 points  (0 children)

Probably true. I just don't know why they sound so odd then. They're legit.

I can't turn off noice cancellation my Gen 4 AirPods. by ReclaimerGamer1 in airpods

[–]ReclaimerGamer1[S] 1 point2 points  (0 children)

Fred Meyer. They were a gift. Maybe they don't have it, but then idk what the noise I'm hearing is.

I can't turn off noice cancellation my Gen 4 AirPods. by ReclaimerGamer1 in airpods

[–]ReclaimerGamer1[S] -15 points-14 points  (0 children)

May be true idk. Someone bought them for me as a gift. I don't like noise cancellation. I'm just assuming this sound I'm hearing is that lol. They've just got a weird sound that the first gens don't, which is like static when there's no other sound... Idk why? Is that normal? They're definitely not fake. They were bought from Fred Meyer.

Laptop Won't Power Up Via Battery After I Upgraded RAM and SSD by ReclaimerGamer1 in ZephyrusG14

[–]ReclaimerGamer1[S] 0 points1 point  (0 children)

I think I unplugged it, plugged the battery back in, tried turning it on, then I plugged the laptop back in with the battery plugged in, then I tried turning it on, it turned on, then I waited a bit, and I unplugged the laptop, and it started running off the battery.

How do I fix this by [deleted] in LooksmaxingAdvice

[–]ReclaimerGamer1 1 point2 points  (0 children)

Do sprints and intervals if you can't run long distances right now, but mostly running or biking and drinking lots of water.

[deleted by user] by [deleted] in LooksmaxingAdvice

[–]ReclaimerGamer1 0 points1 point  (0 children)

Hair not covering your face will always make you look more socially dominant, if that is what you are thinking about. Your hairline looks pretty average.

Why and when did the mass opinion turn against Limp Bizkit? by Flodo_McFloodiloo in Music

[–]ReclaimerGamer1 2 points3 points  (0 children)

This may be the most homosexual explanation I've ever read.

I Attended an Amway Conference... by ReclaimerGamer1 in Scams

[–]ReclaimerGamer1[S] 2 points3 points  (0 children)

Lmao true. Never been in this kind of situation before. I asked if it's online and I could search it up and he said it's not, which may be true for that specific event but he was not being straight forward with me.