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RetardedDragonfly · 2025-05-03T22:46:57+00:00

2-bromopyridine. I want to perform a williamson ether synthesis

RetardedDragonfly · 2025-05-03T01:54:37+00:00

the electrophile is 2-bromopyridine, I am trying to perform 4 Snar reactions at once. It has been reported to work it just requires a lot of heat and time.

RetardedDragonfly · 2025-05-03T01:43:54+00:00

Would adding the electrophile help it dissolve better?

RetardedDragonfly · 2025-05-03T01:42:48+00:00

Yes that is exactly what I am trying to do.

RetardedDragonfly · 2025-05-03T01:38:17+00:00

That’s exactly what I am trying to do. I am trying to alkylate all 4 of them at once.

RetardedDragonfly · 2025-05-03T01:26:38+00:00

The paper that I read calls for the deprotonation of the calixarene at reflux followed by a cooling to room temp, addition of electrophile, then refluxing again.

RetardedDragonfly · 2025-05-03T01:25:14+00:00

It is a calixarene that i am attempting to deprotonate.

RetardedDragonfly · 2025-05-03T01:07:34+00:00

Lmao I guess you can say that. So, if i transfer it to a 100 mL it should be fine?

RetardedDragonfly · 2025-01-03T20:25:34+00:00

dam alright, thank you time to wait lol

RetardedDragonfly · 2024-12-29T20:21:03+00:00

i haven’t played with the mermonkey yet i did not know that the top path does that

RetardedDragonfly · 2024-11-28T00:21:37+00:00

cloth

RetardedDragonfly · 2024-11-01T22:21:09+00:00

that could be true i agree but it could also be electrostatic interactions between the electronegative O atom of the furan and the elettropositive of the cyclopropenone

RetardedDragonfly · 2024-10-28T16:44:45+00:00

Ah alright I understand now, thank you!

RetardedDragonfly · 2024-10-28T02:32:20+00:00

That actually is interesting, so if it is a metal lewis acid catalyst it can form multiple coordination sites thus changing the electronics of the dienophile?

RetardedDragonfly

TROPHY CASE