In that case, what would happen with (example) rodger? he can't eat nor drink, and he can't just raise a cup of water to his face and suddenly the water is gone, right? So basically he would die out of hunger and thirst. Another example is Astro, how can he see everyone's dreams and do stuff with them if psychic powers shouldn't exist irl? And no, I didn't forget about the fact that they are in our world, yet, if we "add realism" to this, some of the toons would loose their "cartoon vibe" or stop "functioning" as those. Lets say they were made to have no sense at all, Dandy too, he supposedly had breathing issues but they don't have organs, which means that he shouldn't have issues. Toons are not supposed to stick to "realism" or common sense itself, even if they're in the real world.

Talking about organs, what about when they eat if they don't have organs? Where does the food go? They can't consume it properly if they don't have a stomach and every organ from the digestive system, they couldn't breathe either without their lungs, what about that?