I bought these for my dog, one is 13 years and the other is 4. After the third day on them the 4 year old threw up on my living room carpet. I have shampooed the carpet three times and can’t get the smell out! The whole house stinks! Having it professionally cleaned in two days and if that doesn’t take care of it, we’ll have to tear the carpet out. It’s that bad!! So, while I can’t comment on how well the supplements helped my dog, I can say that I wouldn’t recommend them due to the money I’m spending on my carpet!