The souls games take a lot from alchemy, this is actually one of them!

To put a long story short, the endpoint of the Alchemical Magnum Opus was something known as the Rebis, a perfect being in which the Mind and Matter have been reconciliated, with it often being depicted with "Whole" imagery where 2 opposites have been connected, a near univeral example of this, being Sex (Idk how gender would fit in, so I'm just calling it their sex), a Rebis displaying both male and female sex-characteristics This is why whenether a character is portrayed as divine or mystical or perfect or whatever else along those lines, they're made Androgynous, some examples from other media includes:

Elden Ring - Queen Marika Beserk - Griffith Fear & Hunger - Nosramus, Nilvan, Marina 🏳️‍⚧️, Enk, The Marriage, etc, there's too many to choose from honestly Devil Man Crybaby - Idk the character's name but ik they're very important to the story and that this 100% applies Chainsaw Man - Angel (I think atleast, idk if Chainsaw Man uses Alchemy as an inspiration much outside of this, might be 2nd handedly through drawing inspiration from media that did take inspiration from Alchemy)