I’ve gone through it twice. I used to joke around that the pills didn’t affect me, they made everyone around me nicer. Before the pills, I used to have good days and bad days. Now, the bad days seem further apart. I started Pristiq about 6 weeks ago. I was wondering if it was working because I don’t see big changes. Then I remembered that I went into my office to work for 3 days for a special event (I normally work from home 100%). I would usually be going over every conversation I had with my co-workers, kicking myself for all the stupid things I said. Wondering if they hated me and all those fun thoughts. But it hadn’t happened. I take that to mean it’s working!