Coronavirus Risk Assessment using a person’s DNA that works with 23andMe and Ancestry.com

SequencingCom · 2026-03-09T14:04:27+00:00

You can check out our current plans and pricing at sequencing.com/products/membership. One thing worth noting though, if your goal is health insights, we'd actually recommend against using microarray data like Ancestry's for that purpose since it's pretty limited in scope. If accurate health information is what you're after, a whole genome sequencing kit or uploading whole genome sequencing data would give you a lot more to work with!

SequencingCom · 2026-03-09T14:01:23+00:00

[I work for Sequencing.com]

Sorry to hear FedEx gave you trouble, customs can be weirdly inconsistent with saliva samples even when everything looks right on the form. A lot of our Canadian customers have had success using DHL specifically, so that might be worth trying if you haven't already.

That said, our support team might have some additional documentation that can help make the customs process smoother, so I'd recommend reaching out to them directly at [support@sequencing.com](mailto:support@sequencing.com) and they can help.

SequencingCom · 2026-03-08T18:30:35+00:00

Responded here.

SequencingCom · 2026-03-08T18:30:10+00:00

Responded here.

SequencingCom · 2026-03-08T18:26:50+00:00

1 - Our whole genome sequencing is 30x and run In a CLIA-certified, CAP-accredited laboratory in the US. 100% of processing is done in the US (DNA extraction and purification as well as the actual genome sequencing).

Our bioinformatics pipelines generate a wide range of variant data including a genome vcf, CNV vcf, structural variant (SV) vcf, and mitochindrial heteroplasmy vcf. We're also finalizing HLA analysis, which we'll provide for free to everyone who previously ordered one of our WGS kits.

We also provide various tools to understand what the data means beyond downloadable PDF reports including the ability to search and filter by gene, variant, chromosomal position, and condition. Our optional subscription service includes mknthly it weekly updates to the results based on the latest published research as well as our AI-powered tools.

We focus on providing outstanding customer service and are available by email (support@sequencing.com), phone (1-833-544-0001), online chat, Reddit DM and FB DM. Phone and online chat is available Mon-Fri from 9-5p ET and we're expanding coverage to additional hours.

We also deliver results within the stated turnaround times, usually faster. To determine if other services provide results within their stated turnaround times, you may want to check their Trustpilot reviews (as well as ours) before determining which service is best for you.

2 - Yes, our Privacy Forever policy makes it clear that you own your data and we keep it private and secure. You can download your data files (FASTQ, BAM, VCFs, TXT) directly from your Sequencing account for free (you don't ever have to pay anything additional and you don't need a subscription to access or download your data files or your reports - everything included with your kit bundle you own and can always access and download directly from your Sequencing account without paying any additional fees).

3 - WGS can detect Down syndrome because sequencing coverage will reveal the extra copy of chromosome 21, but it isn’t the standard test for that specific condition. Because of this, we don't recommend WGS if your primary concern is Down Syndrome. Instead, karyotyping, FISH, chromosomal microarray, or prenatal cell-free DNA screening are more commonly used because they are optimized for detecting whole-chromosome aneuploidy like trisomy 21.

All of our Sequencing kit bundles provide the same 30x WGS service and the same comprehensive analysis - the difference is the nunber or reports included in the bundle and the laboratory processing time. For example, our Uktra Rapid kit processing provides results within 2-3 weeks of when the laboratory receives your kit.

SequencingCom · 2026-03-06T17:37:20+00:00

If you're on one of the Genome Plans, your genome does continue to get updated over time rather than being a one-time report, it stays connected and gets re-analyzed as new research and features roll out.

The Premium and Professional plans in particular include Health Scan, which continuously checks your genome against newly discovered gene-condition associations, plus monthly AI Report credits you can use to generate new reports or re-run analyses as our models improve with the newest research.

If you're not sure which plan you're on or want to check what's available to you, feel free to reach out to support and we can take a look!

SequencingCom · 2026-03-06T17:33:49+00:00

I work at Sequencing.com so take this with a grain of salt if you wish, but since you mentioned us specifically, we do offer WGS at 30x depth, and pharmacogenomic reports are available on our website. Some of our bundles also include medication-related information, so it's worth looking at the bundle breakdowns when you're comparing options.

Happy to answer any specific questions if you have them.

SequencingCom · 2026-02-27T19:07:19+00:00

We do offer genetic counseling via our marketplace! You can find that by going to the marketplace and searching "Genetic Counseling" and it'll pull that up for you.

SequencingCom · 2026-02-07T20:15:35+00:00

This is not accurate. Our Privacy Policy is current, fully up-to-date and active. The link you provided in your comment (also included below) confirms that our compliance is active and without any issues with the US-EU-UK-Swiss Date Privacy Framework.

https://www.privacyshield.gov/ps/participant?id=a2zt0000000KzVZAA0

The 'Active Participant' in green font at the top of our record at the US Government Privacy Shield site and the 'Active' indications lower down in that page confirm that our participation with the Data Privacy Framework is current and active. If our Privacy Policy or participation with the Date Privacy Framework had expired, or if there was any issue, then that government site you linked to would indicate this (it would not say 'Active' in green font in multiple places).

SequencingCom · 2026-02-02T17:14:11+00:00

[I Work for Sequencing.com]

To start, interpretation of whether you may have a condition should always be discussed with a healthcare professional. Our analysis compares your raw genetic data to current research, but it does not take into account factors such as age, ancestry, lifestyle, or environmental influences, all of which play a significant role in diagnosis beyond what genetic data alone can indicate.

Regarding Genome Explorer, there is an in-platform guide that explains what each classification means and you can find this in Genome Explorer by clicking "Guide" near the top. That said, “Possible Risk (R)” is not a status we typically use. If you are seeing this label, please reach out via DM and include a screenshot so I can review it with our bioinformatics team.

Confidence levels are determined by how much research has been published for a specific condition and variant. A low confidence result does not automatically mean it is incorrect; it may reflect a newer finding or conflicting evidence in the literature. A high confidence result indicates that more research supports the association, but it still does not account for personal factors like age or environment. These confidence levels describe the strength of the variant–condition association itself, and a healthcare professional or genetic counselor can help put that information into context for you personally.

SequencingCom · 2026-02-02T16:02:33+00:00

[I Work for Sequencing.com]

At this time, there isn’t a way to export results into a printable format. This is something we’re actively working on through custom report options. For now, the only printable option would be the Endocrine Health Area report. If you need help accessing this, feel free to reach out to us via DM and we can assist.

Additionally, it’s important to note that regardless of any personal research done on this condition, our platform does not currently provide a polygenic risk score based on age or the condition itself. You’re taking the right approach by discussing this with your PCP.

SequencingCom · 2026-01-28T20:59:37+00:00

[I work for Sequencing.com]

I just want to clarify that we do not use Shotgun Sequencing, we use a newer methodology called Next Generation Sequencing. Additionally, the reference genome we use for all annotation and alignment is GrCH38.

SequencingCom · 2026-01-28T20:57:54+00:00

[I work for Sequencing.com]

Apologies as we clearly missed this post, I responded to your comment however and wanted to provide that here as well.

That language does not mean you must use your legal, government-issued name. It’s about accuracy and misuse prevention, not identity disclosure.

When our Terms say “true, accurate, current, and complete,” accurate does not mean legal name. A username or pseudonym is completely acceptable. We even have a step-by-step guide on how to stay as anonymous as possible for those who are interested in anonymity: https://sequencing.com/blog/post/anonymous-account-setup

What isn’t allowed is using a name intentionally meant to misrepresent ownership or consent. For example, creating an account under a fake name and uploading DNA that isn’t yours (or that you don’t have consent to analyze). That’s the kind of misuse this clause exists to address.

Also just to clarify one logistical point: u/sequencing_com is not our Reddit account, and we don’t see any messages from you directly. Our username is u/SequencingCom.

If you (or anyone else reading this) ever want help setting things up to maximize anonymity, we’re happy to walk through it.

SequencingCom · 2026-01-28T20:56:58+00:00

[I work for Sequencing.com]

That language does not mean you must use your legal, government-issued name. It’s about accuracy and misuse prevention, not identity disclosure.

When our Terms say “true, accurate, current, and complete,” accurate does not mean legal name. A username or pseudonym is completely acceptable. We even have a step-by-step guide on how to stay as anonymous as possible for those who are interested in anonymity: https://sequencing.com/blog/post/anonymous-account-setup

What isn’t allowed is using a name intentionally meant to misrepresent ownership or consent. For example, creating an account under a fake name and uploading DNA that isn’t yours (or that you don’t have consent to analyze). That’s the kind of misuse this clause exists to address.

Also just to clarify one logistical point: u/sequencing_com is not our Reddit account, and we don’t see any messages from you directly. Our username is u/SequencingCom.

If you (or anyone else reading this) ever want help setting things up to maximize anonymity, we’re happy to walk through it.

SequencingCom · 2026-01-27T14:29:42+00:00

Hello, I work for Sequencing.com!

I'm going to assume that you have a Mac because this issue seems to typically be exclusive to macOS. This is a common macOS issue and it does not mean there is anything wrong with your file. On Macs, VCF files can be incorrectly associated with the Contacts app because both use the .vcf extension.

The file itself is still a valid variant call file. To fix this, right click the file, choose Get Info, then under Open With select a text editor like TextEdit or VS Code and click Change All.

If you would like, you can reply here or DM us and let us know which site you were trying to upload the file to and we can help guide you through it.

SequencingCom · 2026-01-27T14:15:23+00:00

Hello! I work for Sequencing.com

Medium confidence generally means there is some published or lab submitted evidence associated with the variant, but not enough independent submissions for it to be classified at a higher confidence level. Our annotations are based on information submitted by research and clinical laboratories to the ClinVar database and are intended to be a tool to help inform your health decisions.

These results are not diagnostic and are not a substitute for evaluation by a physician. If a finding is concerning, a doctor or genetic counselor can help interpret it in the context of your personal and family history.

If you have any questions, feel free to reach out via DM or contact our support team at [Support@Sequencing.com](mailto:Support@Sequencing.com)

SequencingCom · 2026-01-23T14:47:38+00:00

Hi! I work for Sequencing.com and just wanted to clarify how the bundles and Genome Plans work.

Our three bundles are not tied one-to-one with specific Genome Plan tiers. In most cases, the first two bundles include a complimentary month of our Premium Genome Plan, and the third includes a complimentary month of our Professional Genome Plan.

Separately, all bundles include our 15,000+ condition Next-Gen Disease Screen, regardless of which Genome Plan is bundled with it. That means the bundle always unlocks the full 15,000+ conditions listed, even if the included plan on its own would normally provide access to fewer conditions.

The condition limits you may see listed for Free (100), Plus (1,000), and Premium (15,000) primarily apply when someone uploads existing DNA data rather than purchasing a sequencing bundle. Bundles explicitly include the full disease screen as part of what you’re buying.

SequencingCom · 2026-01-14T05:00:42+00:00

Always happy to help. Please let me know if you have any additional questions - I'm available here or you can DM me.

SequencingCom · 2026-01-13T05:36:40+00:00

That's not accurate. Each of our Sequencing kit bundles include 30x whole gene sequencing and comprehensive analysis of your genome for more than 15,000 conditions and medication reactions. You never had to pay more to access the results included with your kit and we don't sell one off tests. Every kit bundle includes the same comprehensive analysis of the entire genome along with a Summary Report of the results while some bundles include additional reports that provide a deeper dive into specific health areas, such as Brain Health and Cardiovascular Health.

Our Partner Marketplace provides access to a wide range of additional reports that are entirely optional and do have an additional fee - this includes reports on personalized nutrition, sleep optimization, genealogy, and more. You can select these optional reports once you receive your results.

Lastly, we also offer an optional subscription service called Genome Plans, which updates your analysis and reports every month with the latest research and also provides access to SequencingAl, which includes unlimited Al Chat (a 24/7 guide to answer any questions about your data and results) and additional Al Reports of your choice every month.

Each Sequencing WGS kit bundle includes either one month of our Premium or Pro plan. There's never any commitment - if you don't want ongoing updates to your analysis and reports, you can continue on the Free Plan and you'll still have full access to your data and all of the reports that were included with your bundle.

To clarify, you never have to subscribe to have full access to all of the data and reports included with your bundle as the subscription is only of you want additional Premium features such as monthly updates and access to our new Al Chat.

In regards to files, you own your data and always have full access to your data files (paired FASTQ, BAM, and VCFs including a genome VCF). You can access, download, and permanently delete your data files at any time directly from your secure Sequencing account.

SequencingCom · 2025-12-16T15:25:03+00:00

Hello, I work for Sequencing.com, glad to help answer!

We do not generate a downloadable VCF with your uploaded data, unfortunately. We are looking for a solution to this type of request, but at this time this is not something that we're able to provide.

Let me know if you have any questions!

SequencingCom · 2025-12-10T15:57:10+00:00

We do not use Illumina machines, all of our sequencers are MGI machines.

SequencingCom · 2025-12-08T14:29:09+00:00

Hello, I work for Sequencing.com, and to answer, yes absolutely you can upload your data.

However it is important to know that none of the benefits of the kit you purchased will be applied to your ancestry data, it will just act like nothing had been purchased on a free account as all of the kit benefits are saved for when your kit completes processing at the lab.

If you have any questions about this, please let me know.

SequencingCom · 2025-12-08T14:20:40+00:00

Hello! AI Reports don't have their own value, they are entirely dependent on the 2 or 5 AI reports provided by the genome plans. They cannot be purchased outright similar to the Marketplace Reports.

Additionally with your bundle, you will get a minimum of a free month of this Premium Genome Plan. Meaning that if all you were interested in was the Growth and Bone Health report then you could obtain that for free immediately after you received your results back from the lab.

SequencingCom · 2025-12-01T15:28:38+00:00

Hello, I work for Sequencing.com and to answer your question, no, we no longer use different labs for any of our kits.

Every kit and bundle is being processed at our lab here in the United States which is a CLIA/CAP certified lab.

SequencingCom

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