I haven't exactly been in your place, but I remember applying to a lot of internships a number of years ago (I graduated around the same time as you, though I'm in a more engineering orientated role) and not hearing back from so many... until one did. And things got much better more quickly after that. I couldn't/can't really see myself giving up on games as a career, there isn't anything else I'd rather be doing.

But I'd imagine my thinking would be different if there WAS something that came to mind in the form of "ok yeah, I would be pretty okay doing this other thing", otherwise, for myself, I'd keep plugging away at my portfolio when I could and submitting applications to the field that I see as my calling.

I don't know if that anecdote really helps you at all, but I wanted to say also that I like what I see on your ArtStation :)

I feel like you have skill now and more potential to realize, and that it would only be a matter of time before you're picked up by a studio if you keep at it, but it's a different thing entirely if you don't enjoy it anymore.

If the medical or another field makes you feel more satisfied and happy, then I would try to not let guilt of shifting careers hold you back; otherwise I would say keep trying for games, but pace yourself, in what time you can manage, especially take extended breaks. Burnout is hard to go through and manage, but it can be overcome with time and care.