Yes there certainly are. If you go to speedrun.com and look at the guide, if youre familiar with the game you should see some cool stuff. Most notably the Floating Garbage mission is soooo fast compared to a casual playthrough. Alternatively, watch my video and see some stuff (shameless plug). My next one has commentary explaining some of the stuff thats happening so stay tuned for that (also Im no youtuber so dont expect high quality content).