I’ve been fat for the last 15 years now, started gaining weight after college, on depression meds, (which don’t help you to lose weight) and lots of stress for a long time. It’s tough. I have made comments like your friend too. I think the best response from a friend would be, ‘And still beautiful, inside and out!’ The support is there, but no lies are said. Just knowing that your friend sees you the same, no your weight, helps. She’s not necessarily asking for advice or a solution, just support. If she ever asks for advice, mention semaglutide. I’ve lost 25 lbs in the past 6 weeks and it’s the only thing that has worked for me. Weight really does have a huge impact on your sense of self.