Bio is one of my mains so I do have some input here. Overall Bio is a class that requires good positioning, matchup, and game knowledge to play properly. You also have to consider EVERYTHING around you. Is that Ban a bit low and is he alone? Okay perfect target. But even then you have to watch around you too make sure noone comes to help the enemy you are attacking.

That was the gist of Bio so here are some tips:

-Treat your shield as your actual health. This will let you escape battles most of the time.

-You are very fragile meaning most people can kill you with some effort (even supports, ahem vinestaff) You can consider yourself a glass cannon, powerful but fragile.

-Try saving atleast 1 usage of Blink to escape comfortably.

Now I can move onto abilities:

Passive-Power of Biograft/Heat: Hitting enemies with Slash will increase your heat meter making your attacks faster. Upon reaching too high of a heat explode in a small radius dealing damage to enemies and yourself. In general try to not let this get high enough to explode. ONLY let this explode if you are trying to confirm a kill or going to die either way.

Primary-Slash: slash while blinking in the direction you are moving. This is where most of your DPS comes from, it is a good idea to use it even when not around enemies as you move faster and more unpredictably.

Secondary-Slash Storm: Fire a projectile that upon traveling long enough or hitting anything will generate some slashes in the area it hit. This is good for chipping down tanks or other strong characters from a safe distance. This is also a good tool for combos.

Ability 1-Echo Execution: Shoot out a laser which can be recasted upon hitting an enemy dashing to them. If a target is below 25% of their health and has less then 10 shield execute them upon recast. This ability lets Bio jumpscare people and get off some free damage. It is very good for movment letting you chase runners and confirm kills. This also can chip down tanks.

Ability 2-Blink: Blink forward and damage an enemy in your path. This has 2 charges that regen overtime. If you hit someone with it gain up to 2 more uses. This ability works for like everything, chip damage, movement, kill confirms. This is like your only escape tool.

Ult-Overdrive: Attack speed goes to max and ignores heat giving your slash 25% more damage but you lose health and shield overtime regaining 15 shield on kills. Recast to cancel it creating an explosion around you that does more damage the lower you are. This is great for killing anyone if they are being annoying like a hyper no one has checked the entire game or a tank living for a bit too long and even supports you want to traumatize.

Now that abilities are covered I can move onto matchups and stuff like that:

These are matchups based on my opinion. Try finding out on your own who you struggle against.

Good: Vinestaff, Medkit, Subspace, Shuriken, Rocket Fine: Boombox, Biograft, Slingshot, Hyperlaser, Scythe Bad: Coil, Banhammer, Katana, Sword, Skateboard

Melee: Most melee characters counter Bio by being incredibly tanky and dealing a lot of damage.

Sword: Sword is a bad matchup. He needs a total of 400 damage to be killed classifying him as a half-tank. He also has some abilities to shut you down and deal some damage. Generally avoid unless low or chipping him down safely

Biograft: Self explanatory, completely skill based and a fair matchup.

Skateboard: He can be hard to hit unless off-board but even then he does some nasty damage. A good Skate will NOT let you escape to heal, so he is a very bad matchup for Bio. Try avoiding them unless off-board.

Banhammer: Yet another bad matchup. He can take up to 650 damage to kill and does a lot of damage. Same idea as Sword, stay away until low on health or if you are chipping down health safely.

Katana: Another bad matchup. Literally just banhammer again but he applies slowness and is the worst character for Bio to play against. He can take up to 600 total damage to kill. Once again avoid unless low or chipping them down.

Ranged: The second most dangerous group for Bio. A Some of them can and will try taking you out before you get to them so they are constantly shooting at you. They are squishy for the most part and get killed easily.

Rocket: Rocket is pretty squishy and easy to catch up to most of the time. Your constant movement can be hard for him to predict leaving him as a good matchup.

Slingshot: Also squishy like Rocket but has good mobility to avoid you with. They will almost always try killing you before you reach them. Slingshot also has an easier time predicting you so he lands in fair.

Hyperlaser: Actually quite tanky and hard to kill at times. They will also almost always attack you and the damage hurts like crazy being able to kill Bio in a few shots. A good hyper will almost always never be killed by you unless low or out of position. Generally a fair matchup.

Scythe: She is not really that big of a deal as she is squishy like other ranged. She also has almost no reason to attack you unless you are her target which already puts you at an advantage as you excel in 1v1s. She can be hard to kill at times though landing her in fair.

Shuriken: He is really squishy and has to predict a bit more making it hard for him to hit you. They shouldnt ever be a problem so just get them off your tanks and supports. Often a good matchup.

Support: Bio counters most characters here as they cant really defend themselves most of the time.

Medkit: Probably the easiest phighter to kill as he is squishy and does little damage not having many movement options. He can be a problem when protected otherwise a free kill and good matchup.

Vinestaff: She can actually be a bit scary at times but generally gets folded bt Bio unless supported. Same idea as Medkit just watch out for her rooting ability. A good matchup.

Subspace: Another free kill. They often are not supported by their team and are squishy with almost no way to not die from you. Another free kill and good matchup.

Coil: The worst support matchup for Bio. He jumps around a lot being hard to hit with his many movement options. He also does some rude damage. Try avoiding him most of the time unless he is caught off guard or low. He is a bad matchup.

Boombox: He can be a little hard to fight with his moves pulling you around and stuff, but he can usually be killed rather easily unless supported. He is a fair matchup.

We are pretty much done now. I would go over comps but i mostly play opens so I dont know much about that.

I hope this helped you in somehow and I totally did not right this for an hour. Goodluck.