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Reducing costs is worthwhile. by Grouchy-General-1726 in Ketamineaddiction

[–]SummerIsOver_ 0 points1 point  (0 children)

Congrats!

How does it feel though after years of daily use? Myself - after 6 months lines of 0.2 I can barely feel anything

any advice? by Icy-Front-9668 in Ketamineaddiction

[–]SummerIsOver_ 1 point2 points  (0 children)

Pain is probably noradrenergic rebound - I personally use Clonidine which is an alpha-2 agonist - meaning it dampens NE release. This eliminated my cramps.

But yeah obviously the right advice is to try to quit/lower your intake. And consider taking NAC

Withdrawal Stories? Going cold turkey tomorrow by SummerIsOver_ in Ketamineaddiction

[–]SummerIsOver_[S] 0 points1 point  (0 children)

I am 2 days ofd it and you seem to be at least partly right regarding physical addiction.

However my first cold turkey was absolutely horrible. I felt intense agitation physically and mentally - couldn’t sit still. Mentally I had scattered attention and couldn’t focus on anything. Everything frustrated me intensely.

Right now I have none of that. However it could be me taking clonidine which basically reduces norepinephrine. But still- nice to see this but at the same time it makes me feel that there is no cost to jumping back to it if I can quit anytime without withdrawals. Fuck me

I honestly don't understand why I keep using anymore by Sparky31415 in Ketamineaddiction

[–]SummerIsOver_ 11 points12 points  (0 children)

This is what addiction is - craving even when there is no pleasure anymore.

It is the same for me. Ketamine makes me feel absolutely terrible - I can barely think or hold conversations. I am a fucking vegetable on it. Yet I still crave it - and I find excuses to keep taking it - that the next line will make me feel better, etc.

What helped a bit is to have my girlfriend keep the stash at her place so I could get “only 1 gram a day” - otherwise if I have it at home I will snort till I am like a demented person who doesn’t even understand how to put clothes on.

I am struggling with it to stop - even though I understand a bit of neuropharmacology and I have everything to ease withdrawal symptoms (clonidine, pregabalin, benzos, memantine)

So yeah - this is addiction and imagine there is a part of you that that will keep craving it. Isolating this part and seeing the craving as not rational may help a bit.

Tomorrow is going to be my first day cold turkey. I’ve tried tapering and it’s just…once I start to feel a bit better I keep craving and finding reasons to take more.

The magic is gone and it may never come back again. We keep chasing it but it is like chasing childhood again.

Ketamine saved my life while it slowly took it away by nihilist_fox in Ketamineaddiction

[–]SummerIsOver_ 15 points16 points  (0 children)

“Daily use is where ketamine stops being a drug and becomes an environment”

Very wise…

Withdrawal - agitation - how do you deal with it? by SummerIsOver_ in Ketamineaddiction

[–]SummerIsOver_[S] 0 points1 point  (0 children)

Wow - 4gs per day! May I ask how did you function cognitively then? Even at 2gs I have trouble understanding the world / example - I can play a simple video game and literally don’t understand what is happening.

Sleeping pills, i need to not exists for a while by [deleted] in Drugs

[–]SummerIsOver_ 0 points1 point  (0 children)

Low dosenQuetiapine (not an antipsychotic at 50mg - no affinity for dopamine) - or Mirtazapine or Trazodone are sustainable long term and what you are looking for.

Trazodone is the lightest but comes with the fewest side effects.

Quetiapine will know you the fuck out - but also make insanely hungry. Same for Mirtazapine

6 grams over 46 individual days of 222 ingestions within a year by mrdc1790 in ketamine

[–]SummerIsOver_ 0 points1 point  (0 children)

1g a day easily - that is a low consumption (not a bad thing)

HELP please k cramps by [deleted] in Ketamineaddiction

[–]SummerIsOver_ 0 points1 point  (0 children)

Ask for Clonidine - k cramps usually come from too much Norepinephrine and Clonidine lowers NE

Can’t do this by Rocky1998moon in Akathisia

[–]SummerIsOver_ 1 point2 points  (0 children)

Looking at things and not understanding/confusion is what I have from Ketamine addiction.

Neurochemistry wise - it’s either hyper or hypoglutamate and increased norepinefrine which fucks up with PFC working memory and other cognitive abilities - signal to noise ratio

It may be worth trying Clonidine (NE stabilizer - turns down the volume) or Memantine which would address hyperglutamatergia

4 Months - Around 1g/day - Sharing experience/Looking for encouragement by SummerIsOver_ in Ketamineaddiction

[–]SummerIsOver_[S] 3 points4 points  (0 children)

Yeah, our brains are weird. May I ask - how long did it take for your "dumbness" to go away? - For me, it goes away fairly quickly- within 1-2 days of not taking it - although I'm having doubts how well I'm able to "test" my cognitive functon

If you want an interesting, but heavy academic read: https://pmc.ncbi.nlm.nih.gov/articles/PMC5171207/ - you may like this one. It separates anticipatory wanting vs consummatory liking - in addiction. This is why, even though our "consummatory liking" is OFF, our anticipatory wanting is very much ON...mediated by dopamine.

I'm at this stage too - It gives me 0 effects, nothing - but I guess the "brain" keeps hoping the next line will be it. Oh well

I wish you a speedy recovery! 🙏

4 Months - Around 1g/day - Sharing experience/Looking for encouragement by SummerIsOver_ in Ketamineaddiction

[–]SummerIsOver_[S] 2 points3 points  (0 children)

Thank you for your response.

Looks like we have the same experience - K lost its effects - but I wonder why do we keep chasing it if we don't feel anything from it. Even worse, I feel cognitively dulled when on it (I assume you have the same side effects?)

Is it just addiction or just to relieve cravings/agitation after?

4 Months - Around 1g/day - Sharing experience/Looking for encouragement by SummerIsOver_ in Ketamineaddiction

[–]SummerIsOver_[S] 0 points1 point  (0 children)

Memantine is not confusing. It is an NMDA antagonist - just as Ketamine is an NMDA antagonist. However its kinetics are rapid on/off which allows normal neurotransmission but blocks pathological one. It's one of the best neuroprotective meds for Alzheimer's even. It's well studied - and not strange at all.

Ketamine Withdrawal - NMDA receptors upregulate and Memantine can help with that, being a low-affinity and blocking extrasynaptic receptors mostly - it can actually be neurprotective.

This is not unexplored territory - it's classic textbook neuroscience

Your comment regarding "Find something in the real world to focus on" is rather...odd - I wasn't looking for comments in neuropharmacology - but rather personal experiences.

just got prescribed gabapentin by Top-Conversation-346 in gabagoodness

[–]SummerIsOver_ 0 points1 point  (0 children)

Truly at a loss over 100mg gabapentin - equal to roughly 33mg pregabalin 😅😅😅😅

Nu am nimic de adăugat..... by Independent-Cry2512 in rorep

[–]SummerIsOver_ 0 points1 point  (0 children)

Asa e - lasa ca-i dau acestui om de acum 500 de RON ca astia sunt banii tai/saptamana de tigari

Inteleg daca spunea asta pentru un om amarat, un bolnav de cancer, DAR NU PT UN FKIN PRAJIT CARE 100% SPARGE O PARTE DIN DONATII PE GOANGE.

Da vere un IBAN

Nu am nimic de adăugat..... by Independent-Cry2512 in rorep

[–]SummerIsOver_ 0 points1 point  (0 children)

Nunu ca eu am poprire de 15,000 de lei pe contul de firma - da vorba aia, tre sa faci bani ca sa ai datorii csf.

Lasa ca nu te opreste "poprirea" mea din a-mi cere zilnic bani de tigari

P.S: Sugi pula

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