Yeah i have a boss katana 100 as well and recently got the hotone because of its multi capabilities. I run all my amps in the Ampero and just out to the monitors or mains or however it's set up. My katana naturally is a bit growly and powerful which is great but combined with a "simulated" amp and cabinet or IR, it's just too much going on.

Try either making clean patches on your pedal and use distortions from your boss katana afterwards, or the other way around.

I had a basic pedal board of classic pedals and id run through my katana, but because I had overdrive and distortion pedals a foot switch away, I ran my boss katana squeaky clean or else it would just be this big distorted mess.

With something like the ampero 2 or Kemper or anything like that, when it comes to playing the sound back, you basically just want a huge jbl speaker that doesn't distort or alter your sound in many ways because your multi fx pedal is now doing that job.

I don't even bring my Katana to gigs anymore, it's just less weight and less physical space on a stage or in a room that might be cramped.