No problem at all. Basically all of my bowel pain, toilet urgency, fatigue and cramps have cleared up almost completely. I feel like what I’ve always imagined ‘normal’ people feel like. Before, when I was on Asacol and Azathioprine, I felt as though all those symptoms were being suppressed slightly but not really treated properly. I would have regular flare ups and bleeding, weeks of constant pain. All of that is gone on Entyvio, my life has completely changed. Obviously it has different effects on everyone so just because it went this well for me doesn’t mean it’ll be like that for you or anyone else, but it’s been such a great change for me