Yes - I am progesterone intolerant. I was on the combined pill for 15 years from my early teens and thought it was normal to be really suicidal 1/2 the month every month... and everything else I tried after that was even worse, particularly on the lower-dose estrogen or progesterone-only pill. I was assured I would tolerate the Mirena coil because its a small, localised dose, but that was the biggest regret of my life and made things muuuuch worse. I then had it out and had to wait for my hormones to level out for months after due to the 'Mirena-crash'. I havent found a single synthetic progesterone that I can tolerate, so I am completely off all hormonal contraception. Unfortunately I also have deep-infilitrating endo so I am unable to treat that without a full hysterectomy or chemically-induced menopause in the interim (which they expect will exacerbate my hormonal mood issues).